Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRD1 | P41143 | 2/20 | 0.54 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.44 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.44 |
| ▸ | TACR1 | P25103 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | DPP4 | P27487 | 1/20 | 0.41 |
| ▸ | TEAD1 | P28347 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9672127 | 0.86 | NPC1 (0.47) | SMN1; SMN2 | |
| SCHEMBL9670929 | 0.81 | OPRD1 (0.57) | OPRD1 | |
| SCHEMBL9670754 | 0.81 | OPRD1 (0.57) | OPRD1 | |
| SCHEMBL9669607 | 0.81 | OPRM1 (0.59) | — | |
| SCHEMBL10645148 | 0.71 | OPRD1 (0.61) | OPRD1KCNH2HRH3KMT2ASMN1; SMN2 | |
| SCHEMBL9672608 | 0.71 | OPRM1 (0.58) | — | |
| SCHEMBL7641140 | 0.71 | OPRD1 (1.00) | OPRD1KCNH2HRH3 | |
| SCHEMBL6627224 | 0.71 | OPRD1 (1.00) | OPRD1KCNH2HRH3 | |
| Hydrochloric Acid SCHEMBL8438708 | 0.70 | OPRD1 (0.98) | OPRD1KCNH2HRH3 | |
| Hydrochloric Acid SCHEMBL3175234 | 0.70 | OPRD1 (0.98) | OPRD1KCNH2HRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0233793-B1 | DECAHYDROQUINOLINE DERIVATIVES, PROCESS FOR THEIR PREPARATION, INTERMEDIATES FOR THEIR PREPARATION, THEIR USE AS MEDICAMENTS AND COMPOSITIONS CONTAINING THEM | ROUSSEL-UCLAF (FR) | 1992-04-01 | — | — | EP | claimed |