Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | EGFR | P00533 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8172215 | 0.79 | KIF11 (0.31) | — | |
| SCHEMBL1528178 | 0.76 | TDP1 (0.34) | — | |
| SCHEMBL5446883 | 0.75 | ALDH1A1 (0.34) | — | |
| SCHEMBL8871231 | 0.73 | POLB (0.32) | — | |
| SCHEMBL13584750 | 0.72 | LMNA (0.49) | MEN1KMT2AMAPTLMNA | |
| SCHEMBL9034843 | 0.72 | MEN1 (0.38) | MEN1KMT2AMAPTLMNA | |
| SCHEMBL4379263 | 0.69 | KDM4E (0.32) | — | |
| SCHEMBL11159377 | 0.69 | ALDH1A1 (0.33) | — | |
| SCHEMBL3826052 | 0.69 | KCNN4 (0.33) | MEN1KMT2A | |
| SCHEMBL4743087 | 0.69 | KCNN4 (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0506982-A1 | 1-AZABICYCLO 3.2.0]HEPT-2-ENE-2-CARBOXYLIC ACID COMPOUNDS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1992-10-07 | — | — | EP | disclosed |