Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | KCNN4 | O15554 | 3/20 | 0.31 |
| ▸ | PARP1 | P09874 | 1/20 | 0.31 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11864984 | 0.87 | CYP19A1 (0.35) | SMN1; SMN2MAPK1 | |
| SCHEMBL1572521 | 0.84 | KCNN4 (0.40) | SMN1; SMN2KCNN4MAPK1 | |
| SCHEMBL11159377 | 0.77 | ALDH1A1 (0.33) | KCNN4ALDH1A1 | |
| SCHEMBL4743087 | 0.77 | KCNN4 (0.31) | KCNN4 | |
| SCHEMBL3826052 | 0.77 | KCNN4 (0.33) | KDM4EKCNN4ALDH1A1 | |
| SCHEMBL8172215 | 0.73 | KIF11 (0.31) | — | |
| SCHEMBL17242715 | 0.73 | METAP2 (0.38) | KDM4ESMN1; SMN2MAPK1ALDH1A1HSD17B10 | |
| SCHEMBL10364899 | 0.72 | TAAR1 (0.40) | HPGDALDH1A1 | |
| SCHEMBL1528178 | 0.70 | TDP1 (0.34) | — | |
| SCHEMBL9670458 | 0.69 | MEN1 (0.35) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2101762-A1 | NOVEL 2 -IMIDAZOLES AS LIGANDS FOR TRACE AMINE ASSOCIATED RECEPTORS (TAAR) | F. Hoffmann-Roche AG (CH) | 2009-09-23 | — | — | EP | disclosed |
| WO-2008071574-A1 | NOVEL 2 -IMIDAZOLES AS LIGANDS FOR TRACE AMINE ASSOCIATED RECEPTORS (TAAR) | F. HOFFMANN-LA ROCHE AG (CH) | 2008-06-19 | — | — | WO | disclosed |
| US-5459144-A | Enterovirus and rhinovirus antiviral, antiinflammatory and antagonist of platelet activating factor | SCHERING CORPORATION (US) | 1995-10-17 | — | — | US | disclosed |
| EP-0110396-A2 | Iron-tetraphenylporphine complex having phosphocholine group and oxygen adsorbing and desorbing agent | TAIHO PHARMACEUTICAL CO., LTD. (JP) | 1984-06-13 | — | — | EP | disclosed |
| EP-0066884-A2 | Oxygen-adsorbing and desorbing agent | TAIHO PHARMACEUTICAL CO., LTD. (JP) | 1982-12-15 | — | — | EP | disclosed |