Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1D | P28221 | 2/20 | 0.32 |
| ▸ | HTR1B | P28222 | 2/20 | 0.32 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7587763 | 0.69 | HTR1D (0.49) | HTR1DHTR1B | |
| SCHEMBL6581570 | 0.54 | NOTUM (0.39) | NOTUM | |
| SCHEMBL17498090 | 0.53 | GABRA1 (0.41) | NOTUM | |
| SCHEMBL21187595 | 0.52 | GRIA1 (0.46) | NOTUM | |
| SCHEMBL8364082 | 0.52 | NOTUM (0.43) | NOTUM | |
| SCHEMBL14035486 | 0.51 | NOTUM (0.65) | NOTUM | |
| SCHEMBL22600390 | 0.51 | NOTUM (0.42) | NOTUM | |
| SCHEMBL8526283 | 0.51 | NOTUM (0.66) | NOTUM | |
| SCHEMBL19084229 | 0.50 | NOTUM (0.38) | NOTUM | |
| SCHEMBL27771549 | 0.50 | XDH (0.42) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0510068-A1 | NEW CENTRALLY ACTING 6,7,8,9-TETRAHYDRO-3H-BENZ(e)INDOLE HETEROCYCLICS | PHARMACIA & UPJOHN COMPANY (US) | 1992-10-28 | — | — | EP | disclosed |
| WO-1991011435-A2 | NEW CENTRALLY ACTING 6,7,8,9-TETRAHYDRO-3H-BENZ(e)INDOLE HETEROCYCLICS | THE UPJOHN COMPANY (US) | 1991-08-08 | — | — | WO | disclosed |