SCHEMBL9670633

SCHEMBL9670633

Cc1ccc(C(O)(F)F)cc1

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MLYCD O95822 1/20 0.52
TSHR P16473 1/20 0.50
CA2 P00918 2/20 0.46
CA1 P00915 1/20 0.46
CA5A P35218 1/20 0.46
CA9 Q16790 1/20 0.46
CYP19A1 P11511 1/20 0.45
ACHE P22303 3/20 0.44
TDP1 Q9NUW8 1/20 0.44
KMT2A Q03164 3/20 0.39
HTT P42858 2/20 0.39
LMNA P02545 2/20 0.39
CYP1A1 P04798 1/20 0.39
CYP1B1 Q16678 1/20 0.39
CYP3A4 P08684 1/20 0.39
CYP2D6 P10635 1/20 0.39
CYP2C9 P11712 1/20 0.39
CYP2C19 P33261 1/20 0.39
NR1H2 P55055 1/20 0.38
NR1H3 Q13133 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13186034 0.93 MLYCD (0.47) MLYCDTSHRCA2CA1CA5A
SCHEMBL31134911 0.85 PGK1 (0.41) TSHRKMT2ANR1H2NR1H3RAB9A
SCHEMBL12562886 0.79 MLYCD (0.53) MLYCDTSHRCA2CA1CA5A
SCHEMBL428959 0.79 MLYCD (0.77) MLYCDNR1H2NR1H3SMN1; SMN2
SCHEMBL11920703 0.77 MLYCD (0.52) MLYCDTSHRCA2NR1H3ALDH1A1
SCHEMBL19941883 0.77 TSHR (0.50) MLYCDTSHRCA2CA1CA5A
SCHEMBL25489552 0.77 CYP1A1 (0.47) MLYCDTSHRCA2CA1CA5A
SCHEMBL5530921 0.77 MLYCD (0.52) MLYCDTSHRCA2NR1H3ALDH1A1
SCHEMBL25489564 0.77 TSHR (0.55) MLYCDTSHRCA2CA1CA5A
SCHEMBL6239612 0.77 TSHR (0.55) MLYCDTSHRCA2CA1CA5A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0485837-A2 Polycarbonate-polysiloxane copolymers with fluoralkylphenoxy end groups BAYER AG (DE) 1992-05-20 EP disclosed