Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | PKM | P14618 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | BLM | P54132 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | CDK2 | P24941 | 1/20 | 0.44 |
| ▸ | MYC | P01106 | 1/20 | 0.42 |
| ▸ | MAX | P61244 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 5/20 | 0.41 |
| ▸ | CA1 | P00915 | 4/20 | 0.41 |
| ▸ | CA9 | Q16790 | 4/20 | 0.41 |
| ▸ | FTO | Q9C0B1 | 1/20 | 0.38 |
| ▸ | AURKA | O14965 | 1/20 | 0.38 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | CA12 | O43570 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5142239 | 0.81 | CDK2 (0.56) | HSD17B10CYP1A2KDM4ETP53MAPT | |
| Nbqx SCHEMBL220464 | 0.81 | MAPT (0.74) | HSD17B10CYP1A2KDM4ETP53MAPT | |
| Nbqx SCHEMBL29412437 | 0.81 | MAPT (0.74) | HSD17B10CYP1A2KDM4ETP53MAPT | |
| Nbqx SCHEMBL30728067 | 0.80 | MAPT (0.73) | HSD17B10CYP1A2KDM4ETP53MAPT | |
| Nbqx SCHEMBL26985644 | 0.80 | MAPT (0.73) | HSD17B10CYP1A2KDM4ETP53MAPT | |
| SCHEMBL9669736 | 0.80 | MYC (0.50) | HSD17B10CYP1A2KDM4ETP53MAPT | |
| Nbqx SCHEMBL2230845 | 0.75 | MAPT (0.65) | HSD17B10CYP1A2KDM4ETP53MAPT | |
| SCHEMBL9671082 | 0.74 | MYC (0.49) | HSD17B10CYP1A2KDM4ETP53MAPT | |
| SCHEMBL9670672 | 0.71 | TTR (0.47) | HSD17B10CYP1A2HPGDBLMKMT2A | |
| SCHEMBL9341166 | 0.70 | KMT2A (0.61) | HSD17B10CYP1A2KDM4ETP53MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4889855-A | ADMINISTERING GLUTAMATE ANTAGONIST TO INHIBIT HYPERACTIVITY OF EXCITATORY NEUROTRANSMITTERS | A/S FERROSAN (DK) | 1989-12-26 | — | — | US | claimed |
| EP-0283959-B1 | HETEROCYCLIC COMPOUNDS AND THEIR PREPARATION AND USE | NOVO NORDISK A/S (DK) | 1992-01-02 | — | — | EP | disclosed |
| US-4912108-A | Containing hydroxy substitution | A/S FERROSAN (DK) | 1990-03-27 | — | — | US | disclosed |
| US-4889855-A | ADMINISTERING GLUTAMATE ANTAGONIST TO INHIBIT HYPERACTIVITY OF EXCITATORY NEUROTRANSMITTERS | A/S FERROSAN (DK) | 1989-12-26 | — | — | US | disclosed |
| EP-0283959-A1 | Heterocyclic compounds and their preparation and use | NOVO NORDISK A/S (DK) | 1988-09-28 | — | — | EP | disclosed |