Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9671631 | 1.00 | ALOX5 (0.42) | ALOX5SIGMAR1 | |
| SCHEMBL9670950 | 0.90 | GLS2 (0.35) | ALOX5SIGMAR1 | |
| SCHEMBL7295059 | 0.90 | GLS2 (0.35) | ALOX5SIGMAR1 | |
| SCHEMBL9671037 | 0.90 | GLS2 (0.35) | ALOX5SIGMAR1 | |
| SCHEMBL9325034 | 0.90 | GLS2 (0.35) | ALOX5SIGMAR1 | |
| SCHEMBL9671482 | 0.89 | SIGMAR1 (0.33) | ALOX5SIGMAR1 | |
| SCHEMBL9670703 | 0.88 | SIGMAR1 (0.33) | ALOX5SIGMAR1 | |
| SCHEMBL9671496 | 0.88 | TBXA2R (0.36) | ALOX5SIGMAR1 | |
| Benzene SCHEMBL9326381 | 0.88 | ALDH1A1 (0.36) | ALOX5SIGMAR1 | |
| SCHEMBL9671613 | 0.88 | TBXA2R (0.36) | ALOX5SIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0295056-B1 | ANTI-INFLAMMATORY FURANONES | ALLERGAN, INC (US) | 1992-08-05 | — | — | EP | disclosed |
| US-5134128-A | Immunosuppressive and antiproliferative activity for psoriasis and calcium homeostasis | ALLERGAN, INC. (US) | 1992-07-28 | — | — | US | disclosed |
| EP-0295056-A1 | Anti-inflammatory furanones | ALLERGAN, INC (US) | 1988-12-14 | — | — | EP | disclosed |