Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAMPT | P43490 | 2/20 | 0.38 |
| ▸ | VNN1 | O95497 | 1/20 | 0.37 |
| ▸ | CNR1 | P21554 | 2/20 | 0.37 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.34 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.34 |
| ▸ | GLO1 | Q04760 | 1/20 | 0.34 |
| ▸ | SLC40A1 | Q9NP59 | 1/20 | 0.34 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.33 |
| ▸ | STS | P08842 | 1/20 | 0.33 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.33 |
| ▸ | HRH1 | P35367 | 1/20 | 0.33 |
| ▸ | CCR3 | P51677 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9670875 | 0.84 | CNR1 (0.36) | NAMPTCNR1 | |
| SCHEMBL9218292 | 0.83 | NAMPT (0.36) | NAMPTVNN1CNR1ALDH1A1PKM | |
| SCHEMBL9220432 | 0.83 | NAMPT (0.36) | NAMPTVNN1CNR1ALDH1A1PKM | |
| SCHEMBL9671018 | 0.76 | CYP3A4 (0.39) | NAMPTCNR1ALDH1A1PKMGLO1 | |
| SCHEMBL9672533 | 0.74 | SLC6A2 (0.35) | CHRM4ALDH1A1 | |
| SCHEMBL9218286 | 0.73 | NR3C1 (0.37) | NAMPTVNN1CYP11B1CYP11B2GLO1 | |
| SCHEMBL9216178 | 0.71 | MAPK1 (0.39) | NAMPTCNR1ALDH1A1PKM | |
| SCHEMBL9670602 | 0.71 | GAA (0.36) | ALDH1A1 | |
| SCHEMBL9217641 | 0.71 | MAPK1 (0.39) | NAMPTCNR1ALDH1A1PKM | |
| SCHEMBL9879131 | 0.71 | GAA (0.36) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0510028-A1 | THIOFORMAMIDE DERIVATIVES. | RHONE POULENC RORER SA (FR) | 1992-10-28 | — | — | EP | disclosed |