Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 1/20 | 0.36 |
| ▸ | NAMPT | P43490 | 1/20 | 0.36 |
| ▸ | TBXAS1 | P24557 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | IDO1 | P14902 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.33 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.33 |
| ▸ | PDK3 | Q15120 | 1/20 | 0.33 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.33 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9671024 | 0.84 | NAMPT (0.38) | CNR1NAMPT | |
| SCHEMBL9216640 | 0.83 | LMNA (0.35) | CNR1NAMPTTBXAS1LMNASMN1; SMN2 | |
| SCHEMBL9209319 | 0.83 | LMNA (0.35) | CNR1NAMPTTBXAS1LMNASMN1; SMN2 | |
| SCHEMBL9672533 | 0.77 | SLC6A2 (0.35) | HTTHDAC4 | |
| SCHEMBL9670873 | 0.75 | CNR1 (0.39) | CNR1NAMPTLMNASMN1; SMN2TSHR | |
| SCHEMBL9211118 | 0.73 | TBXAS1 (0.40) | NAMPTTBXAS1LMNASMN1; SMN2TSHR | |
| SCHEMBL9211128 | 0.73 | TBXAS1 (0.40) | NAMPTTBXAS1LMNASMN1; SMN2TSHR | |
| SCHEMBL9879131 | 0.73 | GAA (0.36) | TSHRIDO1 | |
| SCHEMBL9670602 | 0.73 | GAA (0.36) | TSHRIDO1 | |
| SCHEMBL9209313 | 0.72 | NAMPT (0.33) | NAMPTLMNASMN1; SMN2TSHRHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0510028-A1 | THIOFORMAMIDE DERIVATIVES. | RHONE POULENC RORER SA (FR) | 1992-10-28 | — | — | EP | disclosed |