Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.35 |
| ▸ | ITGA4 | P13612 | 8/20 | 0.33 |
| ▸ | ITGB7 | P26010 | 8/20 | 0.33 |
| ▸ | IDO1 | P14902 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.32 |
| ▸ | KDM5A | P29375 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.31 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9670602 | 1.00 | GAA (0.36) | GAANPY5RITGA4ITGB7IDO1 | |
| SCHEMBL9209965 | 0.81 | GAA (0.35) | GAANPY5RITGA4ITGB7IDO1 | |
| SCHEMBL9217244 | 0.81 | GAA (0.35) | GAANPY5RITGA4ITGB7IDO1 | |
| SCHEMBL9678400 | 0.74 | P2RX7 (0.43) | GAAITGA4ITGB7IDO1ALDH1A1 | |
| SCHEMBL9212001 | 0.73 | NPY5R (0.34) | GAANPY5RITGA4ITGB7CYP1A2 | |
| SCHEMBL9217487 | 0.73 | NPY5R (0.34) | GAANPY5RITGA4ITGB7CYP1A2 | |
| SCHEMBL9670875 | 0.73 | CNR1 (0.36) | IDO1TSHR | |
| SCHEMBL9211543 | 0.72 | P2RX7 (0.34) | GAAITGA4ITGB7IDO1CYP1A2 | |
| SCHEMBL9670596 | 0.71 | CYP3A4 (0.37) | NPY5RCYP1A2GRIA2HSD17B10ADRB2 | |
| SCHEMBL9671024 | 0.71 | NAMPT (0.38) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1991010652-A1 | THIOFORMAMIDE DERIVATIVES | RHONE-POULENC RORER S.A. (FR) | 1991-07-25 | — | — | WO | disclosed |