Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AGBL2 | Q5U5Z8 | 1/20 | 0.36 |
| ▸ | CRHR1 | P34998 | 1/20 | 0.34 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.31 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.31 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.31 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.31 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.31 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30255466 | 0.69 | AGBL2 (0.36) | AGBL2CRHR1GABRA1GABRG2GABRB3 | |
| SCHEMBL9672080 | 0.68 | KMT2A (0.39) | AGBL2CRHR1GABRA1GABRG2GABRB3 | |
| SCHEMBL20911927 | 0.67 | AGBL2 (0.40) | AGBL2CRHR1GABRA1GABRG2GABRB3 | |
| SCHEMBL28679434 | 0.67 | KDM4E (0.49) | GABRG2GABRB3GABRA5GABRA3 | |
| SCHEMBL2083869 | 0.64 | — | — | |
| SCHEMBL16493300 | 0.64 | — | — | |
| SCHEMBL27241020 | 0.63 | CYP17A1 (0.41) | — | |
| SCHEMBL15624387 | 0.63 | GABRG2 (0.43) | AGBL2GABRA1GABRG2GABRB3GABRA5 | |
| SCHEMBL12306482 | 0.62 | CCR1 (0.39) | — | |
| SCHEMBL26266903 | 0.62 | ACLY (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5153211-A | Enzyme inhibitors | ALCON LABORATORIES, INC. (US) | 1992-10-06 | — | — | US | disclosed |
| US-5070100-A | COMPLICATIONS OF DIABETES | ALCON LABORATORIES, INC. (US) | 1991-12-03 | — | — | US | disclosed |
| US-4864028-A | ANTIDIABETIC AGENTS | ALCON LABORATORIES, INC. (US) | 1989-09-05 | — | — | US | disclosed |