Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA1A | P35348 | 1/20 | 0.59 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.59 |
| ▸ | AHR | P35869 | 1/20 | 0.32 |
| ▸ | CYP26A1 | O43174 | 2/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6415097 | 0.80 | AHR (0.35) | ADRA1APDE4DAHRCYP26A1ALDH1A1 | |
| Malotilate SCHEMBL635496 | 0.76 | ADRA1A (1.00) | ADRA1APDE4D | |
| SCHEMBL9674429 | 0.72 | ADRA1A (0.66) | ADRA1APDE4DALDH1A1LMNA | |
| SCHEMBL8055886 | 0.72 | ADRA1A (0.82) | ADRA1APDE4D | |
| SCHEMBL9706734 | 0.70 | ADRA1A (0.79) | ADRA1APDE4DALDH1A1 | |
| SCHEMBL9673062 | 0.70 | ADRA1A (0.62) | ADRA1APDE4D | |
| SCHEMBL2451086 | 0.70 | CYP24A1 (0.38) | AHRCYP26A1ALDH1A1 | |
| SCHEMBL9706763 | 0.69 | ADRA1A (0.60) | ADRA1APDE4DALDH1A1LMNA | |
| SCHEMBL9672809 | 0.68 | ADRA1A (0.59) | ADRA1APDE4DALDH1A1LMNA | |
| SCHEMBL9706771 | 0.68 | ADRA1A (0.74) | ADRA1APDE4D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0298040-B1 | 1,3-DITHIOL-2-YLIDENE DERIVATIVES | YUHAN CORPORATION, LTD. (KR) | 1992-08-26 | — | — | EP | disclosed |