Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA1A | P35348 | 1/20 | 0.79 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.79 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | CA12 | O43570 | 3/20 | 0.31 |
| ▸ | CA1 | P00915 | 3/20 | 0.31 |
| ▸ | CA2 | P00918 | 3/20 | 0.31 |
| ▸ | CA7 | P43166 | 3/20 | 0.31 |
| ▸ | CA9 | Q16790 | 3/20 | 0.31 |
| ▸ | CA14 | Q9ULX7 | 3/20 | 0.31 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Malotilate SCHEMBL635496 | 0.89 | ADRA1A (1.00) | ADRA1APDE4DGAASMN1; SMN2TSHR | |
| SCHEMBL8055886 | 0.84 | ADRA1A (0.82) | ADRA1APDE4DGAASMN1; SMN2TSHR | |
| SCHEMBL9706771 | 0.79 | ADRA1A (0.74) | ADRA1APDE4DGAASMN1; SMN2CA12 | |
| SCHEMBL9523192 | 0.79 | ADRA1A (0.49) | ADRA1APDE4DSMN1; SMN2TSHRALDH1A1 | |
| SCHEMBL8050522 | 0.78 | ADRA1A (0.77) | ADRA1APDE4DGAASMN1; SMN2TSHR | |
| SCHEMBL9706732 | 0.78 | ADRA1A (0.72) | ADRA1APDE4DGAASMN1; SMN2TSHR | |
| Malotilate SCHEMBL5489569 | 0.77 | ADRA1A (0.75) | ADRA1APDE4D | |
| SCHEMBL10614796 | 0.77 | ADRA1A (0.75) | ADRA1APDE4D | |
| SCHEMBL9706745 | 0.77 | ADRA1A (0.75) | ADRA1APDE4D | |
| SCHEMBL9706767 | 0.76 | ADRA1A (0.68) | ADRA1APDE4DALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5158950-A | Treatment of liver disorders | YUHAN CORPORATION, LTD. (KR) | 1992-10-27 | — | — | US | disclosed |
| EP-0298040-A1 | 1,3-Dithiol-2-ylidene derivatives | YUHAN CORPORATION, LTD. (KR) | 1989-01-04 | — | — | EP | disclosed |