Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA1A | P35348 | 1/20 | 0.60 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.60 |
| ▸ | FKBP1A | P62942 | 3/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9674429 | 0.87 | ADRA1A (0.66) | ADRA1APDE4DMEN1KMT2AALDH1A1 | |
| SCHEMBL9673062 | 0.85 | ADRA1A (0.62) | ADRA1APDE4DKMT2ASMN1; SMN2HPGD | |
| SCHEMBL19500122 | 0.77 | SMN1; SMN2 (0.46) | MEN1KMT2AALDH1A1SMN1; SMN2MAPT | |
| Malotilate SCHEMBL635496 | 0.77 | ADRA1A (1.00) | ADRA1APDE4DMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL8055886 | 0.73 | ADRA1A (0.82) | ADRA1APDE4DMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL9706734 | 0.71 | ADRA1A (0.79) | ADRA1APDE4DALDH1A1SMN1; SMN2TSHR | |
| SCHEMBL9673280 | 0.71 | ADRA1A (0.54) | ADRA1APDE4DALDH1A1SMN1; SMN2HPGD | |
| Malotilate SCHEMBL5489569 | 0.70 | ADRA1A (0.75) | ADRA1APDE4D | |
| SCHEMBL9673259 | 0.69 | ADRA1A (0.59) | ADRA1APDE4DALDH1A1LMNA | |
| SCHEMBL9706771 | 0.69 | ADRA1A (0.74) | ADRA1APDE4DSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5158950-A | Treatment of liver disorders | YUHAN CORPORATION, LTD. (KR) | 1992-10-27 | — | — | US | disclosed |