Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TERT | O14746 | 2/20 | 0.56 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.56 |
| ▸ | NPC1 | O15118 | 5/20 | 0.49 |
| ▸ | RAB9A | P51151 | 4/20 | 0.49 |
| ▸ | CA1 | P00915 | 4/20 | 0.49 |
| ▸ | CA9 | Q16790 | 4/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | HTT | P42858 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | L1CAM | P32004 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | RECQL | P46063 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4229962 | 0.92 | TERT (0.63) | TERTALOX5NPC1RAB9ACA1 | |
| SCHEMBL4218154 | 0.86 | CA1 (0.65) | TERTALOX5NPC1RAB9ACA1 | |
| SCHEMBL1436240 | 0.78 | GAA (0.69) | TERTALOX5NPC1CA1ALDH1A1 | |
| SCHEMBL32018464 | 0.78 | TERT (0.61) | TERTALOX5CA1CA9ALDH1A1 | |
| SCHEMBL723254 | 0.78 | TERT (0.61) | TERTALOX5CA1CA9ALDH1A1 | |
| SCHEMBL4230145 | 0.78 | KMT2A (0.63) | TERTNPC1RAB9AALDH1A1KDM4E | |
| SCHEMBL4235075 | 0.78 | LMNA (0.61) | NPC1RAB9AALDH1A1KDM4ESMN1; SMN2 | |
| SCHEMBL4223765 | 0.76 | TLR7 (0.60) | TERTALOX5NPC1RAB9ACA1 | |
| SCHEMBL23117963 | 0.76 | ALOX5 (0.59) | TERTALOX5NPC1CA1CA9 | |
| SCHEMBL8983169 | 0.76 | ALOX5 (0.59) | TERTALOX5NPC1CA1CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0251143-B1 | 2-Oxo-1-[[(Substituted Sulfonyl)Amino]-Carbonyl]Azetidines | Bristol-Myers Squibb GmbH (DE) | 1992-08-26 | — | — | EP | disclosed |
| US-4801705-A | 2-oxo-1-(((substituted sulfonyl)amino)-carbonyl)azetidines | E. R. SQUIBB & SONS, INC. (US) | 1989-01-31 | — | — | US | disclosed |
| EP-0251143-A1 | 2-Oxo-1-[[(Substituted Sulfonyl)Amino]-Carbonyl]Azetidines | Bristol-Myers Squibb GmbH (DE) | 1988-01-07 | — | — | EP | disclosed |