Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | VDR | P11473 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 9/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.39 |
| ▸ | RAB9A | P51151 | 6/20 | 0.39 |
| ▸ | MAPT | P10636 | 5/20 | 0.39 |
| ▸ | NPC1 | O15118 | 5/20 | 0.39 |
| ▸ | PKM | P14618 | 3/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | NOS2 | P35228 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 5/20 | 0.38 |
| ▸ | GAA | P10253 | 4/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.37 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.37 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.37 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.37 |
| ▸ | GLA | P06280 | 3/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1656174 | 0.85 | KDM4E (0.42) | KDM4EALDH1A1RAB9AMAPTNPC1 | |
| SCHEMBL28470187 | 0.78 | NOS2 (0.55) | KDM4EALDH1A1RAB9AMAPTNPC1 | |
| SCHEMBL7191387 | 0.77 | VDR (0.50) | VDRKDM4EALDH1A1RAB9AMAPT | |
| SCHEMBL28363149 | 0.77 | SMN1; SMN2 (0.40) | KDM4EALDH1A1RAB9AMAPTNPC1 | |
| SCHEMBL2082562 | 0.75 | LMNA (0.57) | VDRKDM4EALDH1A1RAB9AMAPT | |
| SCHEMBL27968001 | 0.74 | VDR (0.48) | VDRKDM4EALDH1A1RAB9AMAPT | |
| SCHEMBL102893 | 0.74 | KDM4E (0.64) | KDM4EALDH1A1RAB9AMAPTNPC1 | |
| SCHEMBL8382361 | 0.74 | LMNA (0.38) | KDM4EALDH1A1RAB9AMAPTNPC1 | |
| SCHEMBL2028532 | 0.74 | HTT (0.50) | KDM4EALDH1A1RAB9AMAPTNPC1 | |
| SCHEMBL9675063 | 0.74 | VDR (0.48) | VDRKDM4EALDH1A1RAB9AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0276942-B1 | 6-BETA(SUBSTITUTED)-(S)-HYDROXYMETHYLPENICILLANIC ACIDS AND DERIVATIVES THEREOF | PFIZER INC. (US) | 1992-04-01 | — | — | EP | disclosed |
| US-4782050-A | BACTERICIDES | PFIZER INC. (US) | 1988-11-01 | — | — | US | disclosed |
| EP-0276942-A1 | 6-Beta(substituted)-(S)-hydroxymethylpenicillanic acids and derivatives thereof | PFIZER INC. (US) | 1988-08-03 | — | — | EP | disclosed |