SCHEMBL2082562

SCHEMBL2082562

C=CCn1c(C=O)nc2ccccc21

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ LMNA P02545 1/20 0.57
▸ VDR P11473 2/20 0.56
▸ KDM4E B2RXH2 4/20 0.55
▸ PKM P14618 2/20 0.55
▸ POLB P06746 1/20 0.55
▸ NPSR1 Q6W5P4 1/20 0.55
▸ GAA P10253 1/20 0.55
▸ RAB9A P51151 4/20 0.54
▸ SMN1; SMN2 Q16637 3/20 0.54
▸ ALDH1A1 P00352 3/20 0.54
▸ MAPT P10636 3/20 0.54
▸ HPGD P15428 3/20 0.54
▸ CYP1A2 P05177 2/20 0.54
▸ CYP2C19 P33261 2/20 0.54
▸ CYP3A4 P08684 1/20 0.54
▸ CYP2D6 P10635 1/20 0.54
▸ L3MBTL1 Q9Y468 2/20 0.53
▸ CYP2C9 P11712 1/20 0.53
▸ PTK2B Q14289 1/20 0.53
▸ MEN1 O00255 2/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21749198 0.80 SMN1; SMN2 (0.69) LMNAKDM4EPKMPOLBNPSR1
SCHEMBL21749197 0.80 SMN1; SMN2 (0.69) LMNAKDM4EPKMPOLBNPSR1
SCHEMBL2084256 0.80 VDR (0.52) LMNAVDRKDM4EPKMPOLB
SCHEMBL3616241 0.80 KDM4E (0.65) LMNAVDRKDM4EPKMPOLB
SCHEMBL9674712 0.80 VDR (0.58) LMNAVDRKDM4EPKMPOLB
SCHEMBL4714535 0.78 VDR (0.53) VDRKDM4EPKMNPSR1GAA
SCHEMBL2084701 0.77 VDR (0.72) LMNAVDRKDM4ENPSR1GAA
Hydrochloric Acid SCHEMBL4727347 0.77 VDR (0.56) LMNAVDRKDM4EPKMPOLB
SCHEMBL9866483 0.77 ALDH1A1 (0.67) LMNAVDRKDM4EPKMPOLB
SCHEMBL1668107 0.77 KDM4E (0.64) LMNAKDM4EPKMPOLBNPSR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 117 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118374135-B Antibacterial waterproof high polymer material for tablecloth and preparation method thereof 东莞市悠悠美居家居制造有限公司 2024-12-17 — — CN claimed
CN-118374135-A Antibacterial waterproof high polymer material for tablecloth and preparation method thereof 东莞市悠悠美居家居制造有限公司 2024-07-23 — — CN claimed
US-12378463-B2 Water-based resin with elasticity for applications in cementing and subterranean structures SAUDI ARABIAN OIL COMPANY (SA) 2025-08-05 — — US disclosed
CN-118374135-B Antibacterial waterproof high polymer material for tablecloth and preparation method thereof 东莞市悠悠美居家居制造有限公司 2024-12-17 — — CN disclosed
CN-118374135-B Antibacterial waterproof high polymer material for tablecloth and preparation method thereof 东莞市悠悠美居家居制造有限公司 2024-12-17 — — CN disclosed
CN-118374135-A Antibacterial waterproof high polymer material for tablecloth and preparation method thereof 东莞市悠悠美居家居制造有限公司 2024-07-23 — — CN disclosed
CN-118374135-A Antibacterial waterproof high polymer material for tablecloth and preparation method thereof 东莞市悠悠美居家居制造有限公司 2024-07-23 — — CN disclosed
US-20240093081-A1 WATER-BASED RESIN WITH ELASTICITY FOR APPLICATIONS IN CEMENTING AND SUBTERRANEAN STRUCTURES SAUDI ARABIAN OIL COMPANY (SA) 2024-03-21 — — US disclosed
US-11795367-B2 Water-based resin with elasticity for applications in cementing and subterranean structures SAUDI ARABIAN OIL COMPANY (SA) 2023-10-24 — — US disclosed
US-11708522-B1 Water-based hydrogel polymer composition and methods of treating subterranean formations or cement constructions comprising contaminants SAUDI ARABIAN OIL COMPANY (SA) 2023-07-25 — — US disclosed
US-20220409589-A1 CHEMOKINE RECEPTOR BINDING HETEROCYCLIC COMPOUNDS WITH ENHANCED EFFICACY GENZYME CORP (US) 2022-12-29 — — US disclosed
US-20040209921-A1 CXCR4 chemokine receptor binding comounds ANORMED CORPORATION (CA) 2004-10-21 — — US disclosed
EP-1465889-A1 CHEMOKINE RECEPTOR BINDING HETEROCYCLIC COMPOUNDS WITH ENHANCED EFFICACY AnorMED Inc. (CA) 2004-10-13 — — EP disclosed
US-20040019058-A1 Chemokine receptor binding heterocyclic compounds with enhanced efficacy ANORMED CORPORATION (CA) 2004-01-29 — — US disclosed
US-20030220341-A1 Chemokine receptor binding heterocyclic compounds with enhanced efficacy ANORMED, INC. (CA) 2003-11-27 — — US disclosed
WO-2003055876-A1 CHEMOKINE RECEPTOR BINDING HETEROCYCLIC COMPOUNDS WITH ENHANCED EFFICACY ANORMED INC. (CA) 2003-07-10 — — WO disclosed
CN-1378541-A Inhibitors of c-JUN N-terminal kinase (JNK) and other protein kinases VERTEX PHARMA (US) 2002-11-06 — — CN disclosed
EP-0276942-B1 6-BETA(SUBSTITUTED)-(S)-HYDROXYMETHYLPENICILLANIC ACIDS AND DERIVATIVES THEREOF PFIZER INC. (US) 1992-04-01 — — EP disclosed
US-4782050-A BACTERICIDES PFIZER INC. (US) 1988-11-01 — — US disclosed
EP-0276942-A1 6-Beta(substituted)-(S)-hydroxymethylpenicillanic acids and derivatives thereof PFIZER INC. (US) 1988-08-03 — — EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030220341-A1 Chemokine receptor binding heterocyclic compounds with enhanced efficacy CCR5, CXCR4, CXCR3 LMNA 4459/4885VDR 220/4885KDM4E 2947/4885
US-20220409589-A1 CHEMOKINE RECEPTOR BINDING HETEROCYCLIC COMPOUNDS WITH ENHANCED EFFICACY CCR5, CXCR4, CXCR3 LMNA 4459/4885VDR 220/4885KDM4E 2947/4885
US-20040019058-A1 Chemokine receptor binding heterocyclic compounds with enhanced efficacy CCR5, CXCR4, CXCR3 LMNA 4459/4885VDR 220/4885KDM4E 2947/4885
US-20040209921-A1 CXCR4 chemokine receptor binding comounds CXCR4, CXCR1, CXCR3 LMNA 4525/4885VDR 382/4885KDM4E 3901/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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