Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1C3 | P42330 | 7/20 | 0.47 |
| ▸ | AKR1C2 | P52895 | 7/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | HMGB1 | P09429 | 1/20 | 0.43 |
| ▸ | CXCL12 | P48061 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 3/20 | 0.43 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.43 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.41 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.41 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | APEX1 | P27695 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10462619 | 0.84 | HMGB1 (0.56) | AKR1C3AKR1C2MAPTHMGB1CXCL12 | |
| SCHEMBL1129446 | 0.83 | ALDH1A1 (0.49) | AKR1C2MAPTHMGB1CXCL12MCL1 | |
| SCHEMBL9003455 | 0.83 | KDM4E (0.50) | SMN1; SMN2MAPTPOLBKDM4EALDH1A1 | |
| SCHEMBL9677356 | 0.82 | MAPT (0.50) | AKR1C3AKR1C2SMN1; SMN2MAPTPOLB | |
| SCHEMBL7087887 | 0.82 | HMGB1 (0.47) | AKR1C2MAPTHMGB1CXCL12MCL1 | |
| SCHEMBL5072689 | 0.81 | ESR1 (0.62) | AKR1C2HMGB1CXCL12MCL1KDM4E | |
| SCHEMBL9676222 | 0.79 | NPC1 (0.50) | AKR1C3AKR1C2SMN1; SMN2MAPTALDH1A1 | |
| SCHEMBL9678150 | 0.77 | ALOX5 (0.41) | AKR1C3AKR1C2MAPTPOLBMCL1 | |
| SCHEMBL4400139 | 0.76 | HMGB1 (0.55) | AKR1C3AKR1C2SMN1; SMN2MAPTHMGB1 | |
| SCHEMBL63554 | 0.76 | KDM4E (0.47) | SMN1; SMN2MAPTPOLBMCL1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5096872-A | Colorless basic dye reacts with salicylic acid derivative to form colored image, paper | KANZAKI PAPER MANUFACTURING CO., LTD. (JP) | 1992-03-17 | — | — | US | disclosed |