Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 3/20 | 0.39 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.33 |
| ▸ | CALM1 | P0DP23 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL3770251 | 0.89 | SIGMAR1 (0.34) | HTR6 | |
| Hydrochloric Acid SCHEMBL30143204 | 0.81 | HTR6 (0.34) | HTR6 | |
| Hydrochloric Acid SCHEMBL3775311 | 0.77 | HTR6 (0.39) | HTR6PTPN1CALM1 | |
| Hydrochloric Acid SCHEMBL9568443 | 0.74 | TNKS2 (0.33) | — | |
| Hydrochloric Acid SCHEMBL29710435 | 0.74 | TNKS2 (0.33) | — | |
| Hydrochloric Acid SCHEMBL968097 | 0.73 | HTR6 (0.39) | HTR6PTPN1CALM1 | |
| Hydrochloric Acid SCHEMBL4083691 | 0.71 | HTR6 (0.41) | HTR6PTPN1CALM1 | |
| Hydrochloric Acid SCHEMBL4094360 | 0.71 | HTR6 (0.41) | HTR6PTPN1CALM1 | |
| Hydrochloric Acid SCHEMBL910454 | 0.71 | HTR6 (0.41) | HTR6PTPN1CALM1 | |
| Hydrochloric Acid SCHEMBL29710457 | 0.71 | PTPN1 (0.35) | PTPN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8299195-B2 | Ethylene homopolymer | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2012-10-30 | — | — | US | disclosed |
| US-8258247-B2 | Catalyst component for polymerization of ethylene and process for producing ethylene polymer (2) | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2012-09-04 | — | — | US | disclosed |
| US-20110003950-A1 | CATALYST COMPONENT FOR POLYMERIZATION OF ETHYLENE AND PROCESS FOR PRODUCING ETHYLENE POLYMER (2) | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2011-01-06 | — | — | US | disclosed |
| US-20100324243-A1 | CATALYST COMPONENT FOR POLYMERIZATION OF ETHYLENE AND PROCESS FOR PRODUCING ETHYLENE POLYMER (1) | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2010-12-23 | — | — | US | disclosed |
| US-20100311934-A1 | ETHYLENE HOMOPOLYMER | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2010-12-09 | — | — | US | disclosed |