Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FGFR1 | P11362 | 10/20 | 0.45 |
| ▸ | SRC | P12931 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.38 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.38 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.38 |
| ▸ | KDR | P35968 | 1/20 | 0.37 |
| ▸ | RAD51 | Q06609 | 1/20 | 0.36 |
| ▸ | PLK1 | P53350 | 1/20 | 0.35 |
| ▸ | HTR6 | P50406 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9395886 | 0.85 | FGFR1 (0.40) | FGFR1SRCKDRPLK1 | |
| SCHEMBL9395781 | 0.85 | FGFR1 (0.40) | FGFR1SRCALDH1A1HPGD | |
| SCHEMBL9678510 | 0.77 | FGFR1 (0.47) | FGFR1SRCALDH1A1HPGDMAPK1 | |
| SCHEMBL10701671 | 0.76 | ACSS2 (0.42) | FGFR1ALDH1A1HTTRAD51 | |
| SCHEMBL9694990 | 0.72 | PDGFRB (0.42) | ALDH1A1HPGDHTT | |
| SCHEMBL8504140 | 0.72 | CYP11B1 (0.34) | HPGDMAPK1HTT | |
| SCHEMBL6480755 | 0.70 | PRMT5 (0.38) | ALDH1A1HPGDMAPK1 | |
| SCHEMBL9395894 | 0.68 | PRMT5 (0.46) | ALDH1A1HPGDHTT | |
| SCHEMBL30181389 | 0.65 | NPC1 (0.54) | FGFR1ALDH1A1HTTKDR | |
| SCHEMBL10702557 | 0.64 | FGFR1 (0.35) | FGFR1SRCALDH1A1HPGDHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0174717-B1 | BENZIMIDAZOLES, AND THEIR PRODUCTION FORMULATION AND USE AS GASTRIC ACID SECRETION INHIBITORS | FISONS plc (GB) | 1992-01-22 | — | — | EP | claimed |
| EP-0174717-A1 | Benzimidazoles, and their production formulation and use as gastric acid secretion inhibitors | FISONS plc (GB) | 1986-03-19 | — | — | EP | claimed |
| EP-0174717-B1 | BENZIMIDAZOLES, AND THEIR PRODUCTION FORMULATION AND USE AS GASTRIC ACID SECRETION INHIBITORS | FISONS plc (GB) | 1992-01-22 | — | — | EP | disclosed |
| EP-0174717-A1 | Benzimidazoles, and their production formulation and use as gastric acid secretion inhibitors | FISONS plc (GB) | 1986-03-19 | — | — | EP | disclosed |