Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B1 | P15538 | 1/20 | 0.34 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.34 |
| ▸ | AGER | Q15109 | 2/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.33 |
| ▸ | APAF1 | O14727 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 2/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.30 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.30 |
| ▸ | ASAH1 | Q13510 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8440816 | 0.74 | CYP11B1 (0.36) | CYP11B1CYP11B2AGERHSD17B10MEN1 | |
| SCHEMBL9395886 | 0.73 | FGFR1 (0.40) | SMN1; SMN2TDP1MAPTTSHRLMNA | |
| SCHEMBL9395781 | 0.73 | FGFR1 (0.40) | HSD17B10HPGDSMN1; SMN2MAPTLMNA | |
| SCHEMBL9675803 | 0.72 | FGFR1 (0.45) | HPGDMAPK1HTT | |
| SCHEMBL636638 | 0.70 | CYP11B1 (0.50) | CYP11B1CYP11B2AGERSMN1; SMN2TDP1 | |
| SCHEMBL9560914 | 0.70 | TDP1 (0.46) | CYP11B1CYP11B2HSD17B10MEN1HPGD | |
| Leminoprazole SCHEMBL143740 | 0.68 | ATP4A (0.39) | MEN1KMT2ASMN1; SMN2TDP1MAPT | |
| Leminoprazole SCHEMBL29895760 | 0.68 | ATP4A (0.39) | MEN1KMT2ASMN1; SMN2TDP1MAPT | |
| Leminoprazole SCHEMBL143739 | 0.68 | ATP4A (0.39) | MEN1KMT2ASMN1; SMN2TDP1MAPT | |
| Leminoprazole SCHEMBL19086179 | 0.67 | ATP4A (0.38) | MEN1KMT2ASMN1; SMN2TDP1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5929244-A | TREATING AN ENANTIOMERICALLY ENRICHED PREPARATION OF THE COMPOUND IN FAVOUR OF ITS (+) OR (-)-ENANTIOMER AT ROOM TEMPERATURE OR BELOW WITH A SOLVENT SELECTED FROM KETONES, ESTERS, ALCOHOL, NITRILES, HYROCARBONS, ETHERS, AMIDES | ASTRA AKTIEBOLAG (SE) | 1999-07-27 | — | — | US | claimed |
| US-5929244-A | TREATING AN ENANTIOMERICALLY ENRICHED PREPARATION OF THE COMPOUND IN FAVOUR OF ITS (+) OR (-)-ENANTIOMER AT ROOM TEMPERATURE OR BELOW WITH A SOLVENT SELECTED FROM KETONES, ESTERS, ALCOHOL, NITRILES, HYROCARBONS, ETHERS, AMIDES | ASTRA AKTIEBOLAG (SE) | 1999-07-27 | — | — | US | disclosed |