Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 12/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | SLC40A1 | Q9NP59 | 1/20 | 0.34 |
| ▸ | PKM | P14618 | 3/20 | 0.34 |
| ▸ | PKLR | P30613 | 1/20 | 0.34 |
| ▸ | KAT6A | Q92794 | 1/20 | 0.33 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.33 |
| ▸ | CCKBR | P32239 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9678708 | 0.85 | HTR6 (0.55) | HTR6 | |
| SCHEMBL9678576 | 0.78 | HTR6 (0.42) | HTR6KDM4ESLC40A1KAT6A | |
| SCHEMBL9675404 | 0.77 | HTR6 (0.55) | HTR6 | |
| SCHEMBL9678534 | 0.76 | ALKBH2 (0.43) | HTR6SLC40A1KAT6A | |
| SCHEMBL9678696 | 0.75 | HTR6 (0.40) | HTR6SLC40A1PKMPKLRKAT6A | |
| SCHEMBL9679257 | 0.75 | RIPK1 (0.36) | HTR6KDM4EPKMPKLRKAT6A | |
| SCHEMBL9678657 | 0.74 | CACNA1H (0.39) | SLC40A1PKMPKLRKAT6ACCKBR | |
| SCHEMBL9678734 | 0.74 | CA1 (0.45) | HTR6SLC40A1 | |
| SCHEMBL9677307 | 0.73 | HTR6 (0.43) | HTR6SLC40A1PKMPKLRKAT6A | |
| SCHEMBL9678276 | 0.72 | HTR6 (0.56) | HTR6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0269141-B1 | 1-CARBAMOYL-2-PYRAZOLINE DERIVATIVES HAVING HERBICIDAL ACTIVITY | DUPHAR INTERNATIONAL RESEARCH B.V (NL) | 1992-09-16 | — | — | EP | disclosed |
| US-4927452-A | 1-carbonyl-2-pyrazoline derivatives having herbicidal activity | DUPHAR INTERNATIONAL RESEARCH B.V. (NL) | 1990-05-22 | — | — | US | disclosed |
| EP-0269141-A2 | 1-Carbamoyl-2-pyrazoline derivatives having herbicidal activity | DUPHAR INTERNATIONAL RESEARCH B.V (NL) | 1988-06-01 | — | — | EP | disclosed |