Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CACNA1H | O95180 | 2/20 | 0.39 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.39 |
| ▸ | KAT6A | Q92794 | 2/20 | 0.37 |
| ▸ | TERT | O14746 | 5/20 | 0.35 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.34 |
| ▸ | SLC40A1 | Q9NP59 | 1/20 | 0.34 |
| ▸ | KIF11 | P52732 | 1/20 | 0.34 |
| ▸ | PKM | P14618 | 2/20 | 0.33 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.33 |
| ▸ | PKLR | P30613 | 1/20 | 0.33 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.33 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | CCKBR | P32239 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9677171 | 0.85 | STS (0.45) | CACNA1HCACNA1CTERTRIPK1SLC40A1 | |
| SCHEMBL9676937 | 0.84 | RIPK1 (0.53) | CACNA1HTERTRIPK1KIF11LMNA | |
| SCHEMBL9679257 | 0.79 | RIPK1 (0.36) | KAT6ARIPK1PKMPKLRLMNA | |
| SCHEMBL9677307 | 0.78 | HTR6 (0.43) | KAT6ASLC40A1PKMEPHX2PKLR | |
| SCHEMBL9678856 | 0.77 | P2RY12 (0.42) | RIPK1 | |
| SCHEMBL9675968 | 0.74 | HTR6 (0.44) | KAT6ASLC40A1PKMPKLRCCKBR | |
| SCHEMBL9676571 | 0.73 | POLB (0.38) | KAT6ASLC40A1KIF11PKMPKLR | |
| SCHEMBL9678604 | 0.72 | RIPK1 (0.56) | CACNA1HTERTRIPK1KIF11LMNA | |
| SCHEMBL9679224 | 0.71 | RIPK1 (0.54) | CACNA1HTERTRIPK1KIF11LMNA | |
| SCHEMBL9678772 | 0.71 | STS (0.43) | CACNA1HTERTRIPK1KIF11PKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0269141-B1 | 1-CARBAMOYL-2-PYRAZOLINE DERIVATIVES HAVING HERBICIDAL ACTIVITY | DUPHAR INTERNATIONAL RESEARCH B.V (NL) | 1992-09-16 | — | — | EP | disclosed |
| US-4927452-A | 1-carbonyl-2-pyrazoline derivatives having herbicidal activity | DUPHAR INTERNATIONAL RESEARCH B.V. (NL) | 1990-05-22 | — | — | US | disclosed |
| EP-0269141-A2 | 1-Carbamoyl-2-pyrazoline derivatives having herbicidal activity | DUPHAR INTERNATIONAL RESEARCH B.V (NL) | 1988-06-01 | — | — | EP | disclosed |