Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.57 |
| ▸ | CHRNA7 | P36544 | 4/20 | 0.57 |
| ▸ | CHRNB2 | P17787 | 4/20 | 0.57 |
| ▸ | CHRNA4 | P43681 | 4/20 | 0.57 |
| ▸ | CHRNB4 | P30926 | 2/20 | 0.57 |
| ▸ | CHRNA3 | P32297 | 2/20 | 0.57 |
| ▸ | CHRNA2 | Q15822 | 2/20 | 0.57 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.57 |
| ▸ | LMNA | P02545 | 1/20 | 0.57 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.57 |
| ▸ | PSIP1 | O75475 | 1/20 | 0.57 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.57 |
| ▸ | HTR3B | O95264 | 1/20 | 0.57 |
| ▸ | CHRNA1 | P02708 | 1/20 | 0.57 |
| ▸ | CHRNG | P07510 | 1/20 | 0.57 |
| ▸ | MAPT | P10636 | 1/20 | 0.57 |
| ▸ | CHRNB1 | P11230 | 1/20 | 0.57 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.57 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.57 |
| ▸ | CHRNA5 | P30532 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31019631 | 1.00 | ALDH1A1 (0.57) | ALDH1A1CHRNA7CHRNB2CHRNA4CHRNB4 | |
| SCHEMBL9676349 | 1.00 | ALDH1A1 (0.57) | ALDH1A1CHRNA7CHRNB2CHRNA4CHRNB4 | |
| SCHEMBL30866534 | 1.00 | ALDH1A1 (0.57) | ALDH1A1CHRNA7CHRNB2CHRNA4CHRNB4 | |
| SCHEMBL9676345 | 1.00 | ALDH1A1 (0.57) | ALDH1A1CHRNA7CHRNB2CHRNA4CHRNB4 | |
| SCHEMBL30866551 | 0.99 | ALDH1A1 (0.58) | ALDH1A1CHRNA7CHRNB2CHRNA4CHRNB4 | |
| SCHEMBL9674691 | 0.99 | ALDH1A1 (0.58) | ALDH1A1CHRNA7CHRNB2CHRNA4CHRNB4 | |
| SCHEMBL9674689 | 0.99 | ALDH1A1 (0.58) | ALDH1A1CHRNA7CHRNB2CHRNA4CHRNB4 | |
| SCHEMBL31019612 | 0.99 | ALDH1A1 (0.58) | ALDH1A1CHRNA7CHRNB2CHRNA4CHRNB4 | |
| SCHEMBL9674682 | 0.99 | ALDH1A1 (0.58) | ALDH1A1CHRNA7CHRNB2CHRNA4CHRNB4 | |
| SCHEMBL31344136 | 0.95 | ALDH1A1 (0.59) | ALDH1A1CHRNA7CHRNB2CHRNA4CHRNB4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11964958-B1 | Vaporizable alkaloid compositions and methods of use thereof | Ready Mix Naturals, LLC (US) | 2024-04-23 | — | — | US | claimed |
| US-5015741-A | Insecticides, aphidicides, psychological disorders, sedatives or tranquilizers | PHILIP MORRIS INCORPORATED (US) | 1991-05-14 | — | — | US | claimed |
| US-11964958-B1 | Vaporizable alkaloid compositions and methods of use thereof | Ready Mix Naturals, LLC (US) | 2024-04-23 | — | — | US | disclosed |
| US-5138062-A | Tranquilizers | PHILIP MORRIS INCORPORATED | 1992-08-11 | — | — | US | disclosed |
| US-5015741-A | Insecticides, aphidicides, psychological disorders, sedatives or tranquilizers | PHILIP MORRIS INCORPORATED (US) | 1991-05-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11964958-B1 | Vaporizable alkaloid compositions and methods of use thereof | SRM, SCLY, SMOX | ALDH1A1 842/4885CHRNA7 81/4885CHRNB2 98/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.