Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 2/20 | 0.45 |
| ▸ | STS | P08842 | 1/20 | 0.43 |
| ▸ | ATM | Q13315 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | CNR1 | P21554 | 1/20 | 0.37 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.37 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.37 |
| ▸ | SLC40A1 | Q9NP59 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | CCR1 | P32246 | 1/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | ITGAV | P06756 | 1/20 | 0.33 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.33 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9679153 | 0.86 | HTR6 (0.42) | HTR6CNR1SLC40A1 | |
| SCHEMBL9676946 | 0.85 | FLT1 (0.47) | HTR6GAASLC40A1L3MBTL1PKM | |
| SCHEMBL9678696 | 0.84 | HTR6 (0.40) | HTR6LMNASLC40A1PKMITGB1 | |
| SCHEMBL9678253 | 0.76 | HTR6 (0.47) | HTR6STSATMGAALMNA | |
| SCHEMBL9678519 | 0.75 | POLB (0.40) | HTR6POLBITGB1ITGA4 | |
| SCHEMBL9677152 | 0.74 | HTR6 (0.45) | HTR6STSATMGAALMNA | |
| SCHEMBL11568912 | 0.73 | TAS1R3 (0.56) | GAALMNAMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL9677235 | 0.73 | HTR6 (0.44) | HTR6STSATMGAALMNA | |
| SCHEMBL9677148 | 0.73 | HTR6 (0.42) | HTR6STSATMGAALMNA | |
| SCHEMBL9679238 | 0.72 | MEN1 (0.46) | MEN1KMT2ASLC40A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0269141-B1 | 1-CARBAMOYL-2-PYRAZOLINE DERIVATIVES HAVING HERBICIDAL ACTIVITY | DUPHAR INTERNATIONAL RESEARCH B.V (NL) | 1992-09-16 | — | — | EP | disclosed |
| US-4927452-A | 1-carbonyl-2-pyrazoline derivatives having herbicidal activity | DUPHAR INTERNATIONAL RESEARCH B.V. (NL) | 1990-05-22 | — | — | US | disclosed |