Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 2/20 | 0.47 |
| ▸ | STS | P08842 | 1/20 | 0.44 |
| ▸ | ATM | Q13315 | 2/20 | 0.39 |
| ▸ | CNR1 | P21554 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | PIK3C3 | Q8NEB9 | 1/20 | 0.36 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.36 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.36 |
| ▸ | P2RY12 | Q9H244 | 1/20 | 0.36 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.35 |
| ▸ | MET | P08581 | 1/20 | 0.35 |
| ▸ | SLC40A1 | Q9NP59 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | CXCR2 | P25025 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9678598 | 0.86 | P2RY12 (0.48) | HTR6CNR1GAAP2RY12POLB | |
| SCHEMBL9677307 | 0.85 | HTR6 (0.43) | HTR6EPHX2SLC40A1PKM | |
| SCHEMBL9677152 | 0.84 | HTR6 (0.45) | HTR6STSATMCNR1GAA | |
| SCHEMBL9678257 | 0.80 | HTR6 (0.50) | HTR6GAALMNAP2RY12 | |
| SCHEMBL9678644 | 0.78 | HTR6 (0.42) | HTR6LMNAKMT2ASMN1; SMN2P2RY12 | |
| SCHEMBL9678675 | 0.78 | P2RY12 (0.44) | HTR6GAALMNASMN1; SMN2SLC1A3 | |
| SCHEMBL9677171 | 0.78 | STS (0.45) | HTR6STSATMCNR1GAA | |
| SCHEMBL9676959 | 0.77 | HTR6 (0.41) | HTR6GAAPIK3C3P2RY12EPHX2 | |
| SCHEMBL9677118 | 0.77 | HTR6 (0.40) | HTR6LMNASMN1; SMN2P2RY12 | |
| SCHEMBL9676453 | 0.76 | HTR6 (0.45) | HTR6STSATMCNR1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0269141-B1 | 1-CARBAMOYL-2-PYRAZOLINE DERIVATIVES HAVING HERBICIDAL ACTIVITY | DUPHAR INTERNATIONAL RESEARCH B.V (NL) | 1992-09-16 | — | — | EP | disclosed |
| US-4927452-A | 1-carbonyl-2-pyrazoline derivatives having herbicidal activity | DUPHAR INTERNATIONAL RESEARCH B.V. (NL) | 1990-05-22 | — | — | US | disclosed |
| EP-0269141-A2 | 1-Carbamoyl-2-pyrazoline derivatives having herbicidal activity | DUPHAR INTERNATIONAL RESEARCH B.V (NL) | 1988-06-01 | — | — | EP | disclosed |