Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 2/20 | 0.42 |
| ▸ | CNR1 | P21554 | 1/20 | 0.36 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.36 |
| ▸ | FLT1 | P17948 | 7/20 | 0.35 |
| ▸ | FLT4 | P35916 | 7/20 | 0.35 |
| ▸ | KDR | P35968 | 7/20 | 0.35 |
| ▸ | SLC40A1 | Q9NP59 | 1/20 | 0.34 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.32 |
| ▸ | ACLY | P53396 | 3/20 | 0.32 |
| ▸ | SPR | P35270 | 1/20 | 0.32 |
| ▸ | RORC | P51449 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9676946 | 0.77 | FLT1 (0.47) | HTR6FLT1FLT4KDRSLC40A1 | |
| SCHEMBL9678696 | 0.76 | HTR6 (0.40) | HTR6SLC40A1AKR1C3 | |
| SCHEMBL9678562 | 0.73 | RORC (0.36) | HTR6CNR1HSD11B1RORC | |
| SCHEMBL9678285 | 0.73 | MEN1 (0.34) | HTR6CNR1HSD11B1FLT1FLT4 | |
| SCHEMBL9679238 | 0.67 | MEN1 (0.46) | SLC40A1 | |
| SCHEMBL9678308 | 0.67 | FLT1 (0.33) | CNR1HSD11B1FLT1FLT4KDR | |
| SCHEMBL14534750 | 0.65 | ALDH1A1 (0.42) | FLT1FLT4KDRSLC40A1ACLY | |
| SCHEMBL11568912 | 0.65 | TAS1R3 (0.56) | — | |
| SCHEMBL9678583 | 0.64 | SLC22A12 (0.40) | HTR6 | |
| SCHEMBL9679243 | 0.64 | HTR6 (0.42) | HTR6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0269141-B1 | 1-CARBAMOYL-2-PYRAZOLINE DERIVATIVES HAVING HERBICIDAL ACTIVITY | DUPHAR INTERNATIONAL RESEARCH B.V (NL) | 1992-09-16 | — | — | EP | disclosed |
| US-4927452-A | 1-carbonyl-2-pyrazoline derivatives having herbicidal activity | DUPHAR INTERNATIONAL RESEARCH B.V. (NL) | 1990-05-22 | — | — | US | disclosed |
| EP-0269141-A2 | 1-Carbamoyl-2-pyrazoline derivatives having herbicidal activity | DUPHAR INTERNATIONAL RESEARCH B.V (NL) | 1988-06-01 | — | — | EP | disclosed |