Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | REN | P00797 | 17/20 | 0.63 |
| ▸ | CTSD | P07339 | 3/20 | 0.53 |
| ▸ | BACE1 | P56817 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9676798 | 1.00 | REN (0.63) | RENCTSDBACE1 | |
| SCHEMBL8893459 | 0.81 | REN (0.61) | RENCTSDBACE1 | |
| SCHEMBL10749186 | 0.81 | REN (0.61) | RENCTSDBACE1 | |
| SCHEMBL8893254 | 0.81 | REN (0.67) | RENCTSD | |
| SCHEMBL7370152 | 0.78 | REN (0.56) | RENCTSD | |
| SCHEMBL11023793 | 0.75 | CTSD (0.62) | RENCTSD | |
| SCHEMBL11013919 | 0.75 | REN (0.66) | REN | |
| SCHEMBL11010625 | 0.75 | REN (0.66) | REN | |
| SCHEMBL11025954 | 0.74 | REN (0.67) | RENCTSD | |
| SCHEMBL18888212 | 0.73 | CTSD (0.62) | RENCTSD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0486478-A2 | Renin-inhibiting peptides | THE UPJOHN COMPANY (US) | 1992-05-20 | — | — | EP | disclosed |
| US-4880781-A | HYPOTENSIVE AGENTS | THE UPJOHN COMPANY (US) | 1989-11-14 | — | — | US | disclosed |
| EP-0173481-A2 | Peptides | THE UPJOHN COMPANY (US) | 1986-03-05 | — | — | EP | disclosed |