Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | REN | P00797 | 16/20 | 0.67 |
| ▸ | CTSD | P07339 | 2/20 | 0.58 |
| ▸ | MEN1 | O00255 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.56 |
| ▸ | LMNA | P02545 | 1/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11023793 | 0.95 | CTSD (0.62) | RENCTSD | |
| SCHEMBL8893254 | 0.93 | REN (0.67) | RENCTSD | |
| SCHEMBL8893459 | 0.88 | REN (0.61) | RENCTSD | |
| SCHEMBL10749186 | 0.88 | REN (0.61) | RENCTSD | |
| SCHEMBL10744547 | 0.81 | ALDH1A1 (0.67) | MEN1ALDH1A1LMNAKMT2A | |
| SCHEMBL11028015 | 0.80 | KLK5 (0.84) | REN | |
| SCHEMBL11025093 | 0.79 | REN (0.76) | RENCTSD | |
| SCHEMBL8894396 | 0.78 | REN (0.67) | RENCTSD | |
| SCHEMBL15290564 | 0.78 | PSMB5 (0.64) | RENALDH1A1 | |
| SCHEMBL11023324 | 0.77 | MEN1 (0.48) | RENCTSDMEN1ALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0077029-B1 | RENIN INHIBITORY PEPTIDES | MERCK & CO. INC. (US) | 1985-08-21 | — | — | EP | disclosed |