Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 1/20 | 0.40 |
| ▸ | EDNRA | P25101 | 2/20 | 0.39 |
| ▸ | EDNRB | P24530 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | KLK7 | P49862 | 1/20 | 0.37 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | RECQL | P46063 | 2/20 | 0.36 |
| ▸ | P2RY12 | Q9H244 | 2/20 | 0.35 |
| ▸ | FBP1 | P09467 | 1/20 | 0.35 |
| ▸ | BRD4 | O60885 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9678675 | 0.87 | P2RY12 (0.44) | HTR6KDM4EALDH1A1EPHX2P2RY12 | |
| SCHEMBL9677118 | 0.86 | HTR6 (0.40) | HTR6P2RY12 | |
| SCHEMBL9678476 | 0.85 | KAT6A (0.40) | HTR6EDNRAALDH1A1 | |
| SCHEMBL9678598 | 0.85 | P2RY12 (0.48) | HTR6POLBP2RY12 | |
| SCHEMBL9678605 | 0.82 | KMT2A (0.46) | ALDH1A1EPHX2POLB | |
| SCHEMBL9676435 | 0.82 | CA1 (0.46) | MAPTALDH1A1POLBBRD4 | |
| SCHEMBL9678257 | 0.82 | HTR6 (0.50) | HTR6KDM4EP2RY12 | |
| SCHEMBL9678632 | 0.81 | SMN1; SMN2 (0.48) | ALDH1A1POLB | |
| SCHEMBL9678519 | 0.77 | POLB (0.40) | HTR6EDNRAEDNRBMAPTKDM4E | |
| SCHEMBL9678253 | 0.76 | HTR6 (0.47) | HTR6EPHX2POLBP2RY12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0269141-B1 | 1-CARBAMOYL-2-PYRAZOLINE DERIVATIVES HAVING HERBICIDAL ACTIVITY | DUPHAR INTERNATIONAL RESEARCH B.V (NL) | 1992-09-16 | — | — | EP | disclosed |
| US-4927452-A | 1-carbonyl-2-pyrazoline derivatives having herbicidal activity | DUPHAR INTERNATIONAL RESEARCH B.V. (NL) | 1990-05-22 | — | — | US | disclosed |
| EP-0269141-A2 | 1-Carbamoyl-2-pyrazoline derivatives having herbicidal activity | DUPHAR INTERNATIONAL RESEARCH B.V (NL) | 1988-06-01 | — | — | EP | disclosed |