Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RY12 | Q9H244 | 2/20 | 0.44 |
| ▸ | ALKBH2 | Q6NS38 | 1/20 | 0.42 |
| ▸ | ALKBH3 | Q96Q83 | 1/20 | 0.42 |
| ▸ | FBP1 | P09467 | 1/20 | 0.41 |
| ▸ | JAK2 | O60674 | 1/20 | 0.41 |
| ▸ | HTR6 | P50406 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 4/20 | 0.41 |
| ▸ | CA2 | P00918 | 4/20 | 0.41 |
| ▸ | CA9 | Q16790 | 4/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.41 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.41 |
| ▸ | CA12 | O43570 | 2/20 | 0.40 |
| ▸ | HRH1 | P35367 | 1/20 | 0.40 |
| ▸ | CCR3 | P51677 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | PPARG | P37231 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9677118 | 0.88 | HTR6 (0.40) | P2RY12ALKBH2ALKBH3JAK2HTR6 | |
| SCHEMBL9678476 | 0.87 | KAT6A (0.40) | HTR6SMN1; SMN2TSHRKAT6AALDH1A1 | |
| SCHEMBL9678598 | 0.87 | P2RY12 (0.48) | P2RY12HTR6CA1CA2CA9 | |
| SCHEMBL9676824 | 0.87 | HTR6 (0.40) | P2RY12FBP1HTR6KDM4EEPHX2 | |
| SCHEMBL9676435 | 0.84 | CA1 (0.46) | CA1CA2CA9TDP1LMNA | |
| SCHEMBL9678605 | 0.84 | KMT2A (0.46) | ALKBH2ALKBH3EPHX2KAT6AALDH1A1 | |
| SCHEMBL9678257 | 0.84 | HTR6 (0.50) | P2RY12HTR6CA2KDM4ELMNA | |
| SCHEMBL9678632 | 0.83 | SMN1; SMN2 (0.48) | ALKBH2ALKBH3CA1CA2SMN1; SMN2 | |
| SCHEMBL9678253 | 0.78 | HTR6 (0.47) | P2RY12HTR6SMN1; SMN2SLC1A3SLC1A2 | |
| SCHEMBL9677307 | 0.78 | HTR6 (0.43) | HTR6HTTEPHX2KAT6AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0269141-B1 | 1-CARBAMOYL-2-PYRAZOLINE DERIVATIVES HAVING HERBICIDAL ACTIVITY | DUPHAR INTERNATIONAL RESEARCH B.V (NL) | 1992-09-16 | — | — | EP | disclosed |
| US-4927452-A | 1-carbonyl-2-pyrazoline derivatives having herbicidal activity | DUPHAR INTERNATIONAL RESEARCH B.V. (NL) | 1990-05-22 | — | — | US | disclosed |
| EP-0269141-A2 | 1-Carbamoyl-2-pyrazoline derivatives having herbicidal activity | DUPHAR INTERNATIONAL RESEARCH B.V (NL) | 1988-06-01 | — | — | EP | disclosed |