Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 2/20 | 0.50 |
| ▸ | ENPP1 | P22413 | 4/20 | 0.42 |
| ▸ | P2RY12 | Q9H244 | 3/20 | 0.42 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.42 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.42 |
| ▸ | EGFR | P00533 | 1/20 | 0.41 |
| ▸ | KCNA1 | Q09470 | 1/20 | 0.41 |
| ▸ | KCNAB1 | Q14722 | 1/20 | 0.41 |
| ▸ | ENPP3 | O14638 | 3/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9678675 | 0.84 | P2RY12 (0.44) | HTR6P2RY12CA2GAALMNA | |
| SCHEMBL9677118 | 0.83 | HTR6 (0.40) | HTR6P2RY12LMNA | |
| SCHEMBL9678476 | 0.82 | KAT6A (0.40) | HTR6 | |
| SCHEMBL9677307 | 0.80 | HTR6 (0.43) | HTR6 | |
| SCHEMBL9678253 | 0.80 | HTR6 (0.47) | HTR6P2RY12GAALMNA | |
| SCHEMBL9676435 | 0.79 | CA1 (0.46) | CA2GAALMNA | |
| SCHEMBL9678644 | 0.74 | HTR6 (0.42) | HTR6P2RY12LMNAKDM4E | |
| SCHEMBL9676959 | 0.73 | HTR6 (0.41) | HTR6P2RY12GAA | |
| SCHEMBL9676881 | 0.71 | RIPK1 (0.59) | PTGS2CA2GAALMNA | |
| SCHEMBL367157 | 0.70 | PTGS2 (0.43) | HTR6ENPP1PTGS2PTGS1EGFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0269141-B1 | 1-CARBAMOYL-2-PYRAZOLINE DERIVATIVES HAVING HERBICIDAL ACTIVITY | DUPHAR INTERNATIONAL RESEARCH B.V (NL) | 1992-09-16 | — | — | EP | disclosed |
| US-4927452-A | 1-carbonyl-2-pyrazoline derivatives having herbicidal activity | DUPHAR INTERNATIONAL RESEARCH B.V. (NL) | 1990-05-22 | — | — | US | disclosed |
| EP-0269141-A2 | 1-Carbamoyl-2-pyrazoline derivatives having herbicidal activity | DUPHAR INTERNATIONAL RESEARCH B.V (NL) | 1988-06-01 | — | — | EP | disclosed |