Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EDNRA | P25101 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | KAT6A | Q92794 | 12/20 | 0.39 |
| ▸ | EDNRB | P24530 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | CNR1 | P21554 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9676571 | 0.87 | POLB (0.38) | POLBKAT6A | |
| SCHEMBL9678305 | 0.86 | FLT1 (0.43) | EDNRAPOLBEDNRBTSHRCNR1 | |
| SCHEMBL9676113 | 0.84 | ALDH1A1 (0.41) | KAT6A | |
| SCHEMBL9676037 | 0.83 | CA1 (0.44) | POLB | |
| SCHEMBL9676148 | 0.82 | SLC22A12 (0.35) | POLB | |
| SCHEMBL9676160 | 0.82 | ALPL (0.39) | — | |
| SCHEMBL9678269 | 0.81 | CCR4 (0.39) | TSHR | |
| SCHEMBL9678624 | 0.80 | KAT6A (0.39) | EDNRAKAT6AEDNRBTSHRCNR1 | |
| SCHEMBL9679161 | 0.78 | L3MBTL1 (0.33) | POLB | |
| SCHEMBL9677074 | 0.77 | STS (0.40) | POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0269141-B1 | 1-CARBAMOYL-2-PYRAZOLINE DERIVATIVES HAVING HERBICIDAL ACTIVITY | DUPHAR INTERNATIONAL RESEARCH B.V (NL) | 1992-09-16 | — | — | EP | disclosed |
| US-4927452-A | 1-carbonyl-2-pyrazoline derivatives having herbicidal activity | DUPHAR INTERNATIONAL RESEARCH B.V. (NL) | 1990-05-22 | — | — | US | disclosed |
| EP-0269141-A2 | 1-Carbamoyl-2-pyrazoline derivatives having herbicidal activity | DUPHAR INTERNATIONAL RESEARCH B.V (NL) | 1988-06-01 | — | — | EP | disclosed |