Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 3/20 | 0.38 |
| ▸ | KAT6A | Q92794 | 3/20 | 0.37 |
| ▸ | KIF11 | P52732 | 1/20 | 0.34 |
| ▸ | PKM | P14618 | 4/20 | 0.33 |
| ▸ | PKLR | P30613 | 1/20 | 0.33 |
| ▸ | CCKBR | P32239 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.32 |
| ▸ | SLC40A1 | Q9NP59 | 1/20 | 0.32 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9677170 | 0.87 | EDNRA (0.40) | POLBKAT6A | |
| SCHEMBL9677074 | 0.85 | STS (0.40) | POLBPKMMEN1KMT2AGAA | |
| SCHEMBL9678590 | 0.79 | PKM (0.34) | KAT6APKMPKLRCCKBRSLC40A1 | |
| SCHEMBL9678308 | 0.78 | FLT1 (0.33) | POLBHSD11B1LMNA | |
| SCHEMBL9678305 | 0.77 | FLT1 (0.43) | POLBGAA | |
| SCHEMBL9677307 | 0.75 | HTR6 (0.43) | KAT6APKMPKLRCCKBRSLC40A1 | |
| SCHEMBL9676037 | 0.74 | CA1 (0.44) | POLBMEN1KMT2ASLC40A1GAA | |
| SCHEMBL9676160 | 0.74 | ALPL (0.39) | PIK3CASLC40A1HSD11B1 | |
| SCHEMBL9676148 | 0.74 | SLC22A12 (0.35) | POLBMEN1KMT2AGAALMNA | |
| SCHEMBL9678657 | 0.73 | CACNA1H (0.39) | KAT6AKIF11PKMPKLRCCKBR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0269141-B1 | 1-CARBAMOYL-2-PYRAZOLINE DERIVATIVES HAVING HERBICIDAL ACTIVITY | DUPHAR INTERNATIONAL RESEARCH B.V (NL) | 1992-09-16 | — | — | EP | disclosed |
| US-4927452-A | 1-carbonyl-2-pyrazoline derivatives having herbicidal activity | DUPHAR INTERNATIONAL RESEARCH B.V. (NL) | 1990-05-22 | — | — | US | disclosed |
| EP-0269141-A2 | 1-Carbamoyl-2-pyrazoline derivatives having herbicidal activity | DUPHAR INTERNATIONAL RESEARCH B.V (NL) | 1988-06-01 | — | — | EP | disclosed |