Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR2 | O15552 | 1/20 | 0.39 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.34 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.33 |
| ▸ | GRM5 | P41594 | 1/20 | 0.33 |
| ▸ | IDH1 | O75874 | 1/20 | 0.33 |
| ▸ | CHKA | P35790 | 1/20 | 0.33 |
| ▸ | RHOC | P08134 | 1/20 | 0.33 |
| ▸ | RHOA | P61586 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | CDK8 | P49336 | 1/20 | 0.33 |
| ▸ | CDK19 | Q9BWU1 | 1/20 | 0.33 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.33 |
| ▸ | DAO | P14920 | 1/20 | 0.32 |
| ▸ | FABP4 | P15090 | 1/20 | 0.32 |
| ▸ | FABP5 | Q01469 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9675023 | 0.91 | FFAR2 (0.40) | FFAR2TRPM8IRAK4GRM5IDH1 | |
| SCHEMBL3159540 | 0.87 | IDH1 (0.39) | FFAR2TRPM8IRAK4GRM5IDH1 | |
| SCHEMBL24917501 | 0.80 | DAO (0.33) | FFAR2RHOCRHOANPSR1DAO | |
| SCHEMBL577680 | 0.74 | CYP3A4 (0.39) | FFAR2IRAK4GRM5CHKACDK8 | |
| SCHEMBL31555059 | 0.72 | CYP1A2 (0.37) | KDM4ENPC1MEN1KMT2A | |
| SCHEMBL312511 | 0.72 | FABP4 (0.36) | FFAR2IRAK4DAOFABP4FABP5 | |
| SCHEMBL25427876 | 0.71 | — | — | |
| SCHEMBL578067 | 0.70 | FFAR2 (0.38) | FFAR2IRAK4GRM5P2RX7FABP4 | |
| SCHEMBL25427246 | 0.70 | — | — | |
| Acetic Acid SCHEMBL15573175 | 0.70 | MEN1 (0.35) | FFAR2IRAK4CDK8CDK19FABP4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0279239-B1 | MICROBICIDES | CIBA-GEIGY AG (CH) | 1992-11-11 | — | — | EP | claimed |
| EP-0279239-A1 | Microbicides | CIBA-GEIGY AG (CH) | 1988-08-24 | — | — | EP | claimed |