SCHEMBL24917501

SCHEMBL24917501

O=C(O)C(F)(F)c1csc(Cl)n1

nearest known ligand 0.33

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
DAO P14920 2/20 0.33
KDM4E B2RXH2 3/20 0.33
NPC1 O15118 3/20 0.33
TDP1 Q9NUW8 1/20 0.33
FFAR2 O15552 1/20 0.32
RHOC P08134 1/20 0.31
RHOA P61586 1/20 0.31
RAB9A P51151 2/20 0.30
MEN1 O00255 1/20 0.30
KMT2A Q03164 1/20 0.30
SMN1; SMN2 Q16637 1/20 0.30
LMNA P02545 1/20 0.30
HTT P42858 1/20 0.30
NPSR1 Q6W5P4 1/20 0.30
HSD17B10 Q99714 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25427876 0.89
SCHEMBL9675023 0.81 FFAR2 (0.40) DAOKDM4ENPC1TDP1FFAR2
Carbamic Acid SCHEMBL9677239 0.80 FFAR2 (0.39) DAOKDM4ENPC1TDP1FFAR2
SCHEMBL24917625 0.79 HDAC3 (0.35) KDM4ENPC1RAB9ASMN1; SMN2HTT
SCHEMBL24917626 0.78 IDH1 (0.31) KDM4ENPC1RAB9ASMN1; SMN2
SCHEMBL20640303 0.78 GABRA5 (0.44) KDM4ENPC1RAB9AMEN1KMT2A
SCHEMBL31555059 0.77 CYP1A2 (0.37) KDM4ENPC1RAB9AMEN1KMT2A
SCHEMBL30527974 0.77 ECE1 (0.40) KDM4EMEN1KMT2ANPSR1
SCHEMBL25427966 0.76 TSHR (0.42) DAOKDM4ENPC1RAB9AMEN1
SCHEMBL3159540 0.76 IDH1 (0.39) KDM4EFFAR2MEN1KMT2ALMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118647270-A Novel derivatives of non-coding amino acids and their use as herbicides 福提费斯特有限公司 2024-09-13 CN claimed
WO-2023131951-A1 NOVEL DERIVATIVES OF NON-CODED AMINO ACIDS AND THEIR USE AS HERBICIDES FORTEPHEST LTD. (IL) 2023-07-13 WO claimed
CN-118647270-A Novel derivatives of non-coding amino acids and their use as herbicides 福提费斯特有限公司 2024-09-13 CN disclosed
US-20240284907-A1 NOVEL DERIVATIVES OF NON-CODED AMINO ACIDS AND THEIR USE AS HERBICIDES FORTEPHEST LTD. (IL) 2024-08-29 US disclosed
EP-4369933-A1 NOVEL DERIVATIVES OF NON-CODED AMINO ACIDS AND THEIR USE AS HERBICIDES Fortephest Ltd. (IL) 2024-05-22 EP disclosed
WO-2023131951-A1 NOVEL DERIVATIVES OF NON-CODED AMINO ACIDS AND THEIR USE AS HERBICIDES FORTEPHEST LTD. (IL) 2023-07-13 WO disclosed
WO-2023286057-A1 NOVEL DERIVATIVES OF NON-CODED AMINO ACIDS AND THEIR USE AS HERBICIDES FORTEPHEST LTD (IL) 2023-01-19 WO disclosed
WO-2023286057-A1 NOVEL DERIVATIVES OF NON-CODED AMINO ACIDS AND THEIR USE AS HERBICIDES FORTEPHEST LTD (IL) 2023-01-19 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240284907-A1 NOVEL DERIVATIVES OF NON-CODED AMINO ACIDS AND THEIR USE AS HERBICIDES DDT, DDC, GLUL DAO 7/4885KDM4E 388/4885NPC1 4849/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.