Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGLL | Q99685 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 2/20 | 0.45 |
| ▸ | ELANE | P08246 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.43 |
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.40 |
| ▸ | ESR1 | P03372 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1223003 | 0.70 | GRM2 (0.67) | GRM2 | |
| SCHEMBL8941864 | 0.70 | HSD11B1 (0.43) | MGLLPOLBELANEMEN1KMT2A | |
| SCHEMBL1223001 | 0.70 | GRM2 (0.67) | GRM2 | |
| SCHEMBL10919797 | 0.66 | MAOA (0.51) | ALDH1A1MAPTTSHRGAA | |
| SCHEMBL12616362 | 0.66 | HSD11B1 (0.51) | MGLLELANEALDH1A1L3MBTL1 | |
| SCHEMBL7294352 | 0.65 | GRM2 (0.71) | GRM2 | |
| SCHEMBL16786672 | 0.65 | MEN1 (0.56) | MGLLPOLBELANEALDH1A1MEN1 | |
| SCHEMBL22571115 | 0.65 | ALDH1A1 (0.59) | POLBALDH1A1MEN1KMT2AMAPT | |
| SCHEMBL8636371 | 0.65 | ALDH1A1 (0.59) | POLBALDH1A1MEN1KMT2AMAPT | |
| SCHEMBL13186564 | 0.65 | ALDH1A1 (0.69) | MGLLPOLBELANEALDH1A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0300272-B1 | OXAZOLIDINONES | MERCK PATENT GmbH (DE) | 1992-09-16 | — | — | EP | disclosed |
| EP-0300272-A1 | Oxazolidinones | MERCK PATENT GmbH (DE) | 1989-01-25 | — | — | EP | disclosed |