Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9678765 | 0.90 | GRM2 (0.56) | SIGMAR1GRM2 | |
| SCHEMBL9844329 | 0.90 | SIGMAR1 (0.54) | SIGMAR1GRM2 | |
| SCHEMBL9677080 | 0.90 | MEN1 (0.52) | SIGMAR1GRM2 | |
| SCHEMBL9676115 | 0.88 | SIGMAR1 (0.54) | SIGMAR1 | |
| SCHEMBL9678985 | 0.87 | SIGMAR1 (0.52) | SIGMAR1GRM2 | |
| SCHEMBL9678371 | 0.87 | SIGMAR1 (0.52) | SIGMAR1 | |
| SCHEMBL9679094 | 0.84 | HTR1A (0.46) | SIGMAR1 | |
| SCHEMBL9677377 | 0.84 | SIGMAR1 (0.71) | SIGMAR1GRM2 | |
| SCHEMBL8800469 | 0.83 | SIGMAR1 (0.66) | SIGMAR1GRM2 | |
| SCHEMBL9086861 | 0.83 | SIGMAR1 (0.66) | SIGMAR1GRM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0300272-B1 | OXAZOLIDINONES | MERCK PATENT GmbH (DE) | 1992-09-16 | — | — | EP | disclosed |
| US-4970217-A | NEUROLEPTIC | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1990-11-13 | — | — | US | disclosed |
| EP-0300272-A1 | Oxazolidinones | MERCK PATENT GmbH (DE) | 1989-01-25 | — | — | EP | disclosed |