Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 6/20 | 0.52 |
| ▸ | GRM2 | Q14416 | 4/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | MGLL | Q99685 | 2/20 | 0.49 |
| ▸ | F10 | P00742 | 4/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | HTR2A | P28223 | 1/20 | 0.45 |
| ▸ | ITGB3 | P05106 | 2/20 | 0.44 |
| ▸ | ITGA2B | P08514 | 2/20 | 0.44 |
| ▸ | F2 | P00734 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9677080 | 0.92 | MEN1 (0.52) | SIGMAR1GRM2MEN1KMT2AF10 | |
| SCHEMBL9844055 | 0.90 | GRM2 (0.49) | GRM2MEN1KMT2AMGLLF10 | |
| SCHEMBL9678371 | 0.90 | SIGMAR1 (0.52) | SIGMAR1LMNAHTR2A | |
| SCHEMBL9677516 | 0.87 | SIGMAR1 (0.66) | SIGMAR1GRM2 | |
| SCHEMBL9678807 | 0.83 | MAOA (0.58) | SIGMAR1GRM2MEN1KMT2AMGLL | |
| SCHEMBL9676115 | 0.82 | SIGMAR1 (0.54) | SIGMAR1HTR2AITGB3ITGA2B | |
| SCHEMBL9844499 | 0.82 | HTR2A (0.53) | GRM2MEN1KMT2ALMNAHTR2A | |
| SCHEMBL9678765 | 0.81 | GRM2 (0.56) | SIGMAR1GRM2MGLL | |
| SCHEMBL7529065 | 0.81 | GRM2 (0.57) | SIGMAR1GRM2 | |
| SCHEMBL9677253 | 0.81 | GRM2 (0.57) | SIGMAR1GRM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0300272-B1 | OXAZOLIDINONES | MERCK PATENT GmbH (DE) | 1992-09-16 | — | — | EP | disclosed |
| US-4970217-A | NEUROLEPTIC | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1990-11-13 | — | — | US | disclosed |
| EP-0300272-A1 | Oxazolidinones | MERCK PATENT GmbH (DE) | 1989-01-25 | — | — | EP | disclosed |