Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 11/20 | 0.54 |
| ▸ | GRM2 | Q14416 | 3/20 | 0.53 |
| ▸ | SLC18A3 | Q16572 | 2/20 | 0.47 |
| ▸ | HTR1A | P08908 | 1/20 | 0.46 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.46 |
| ▸ | HTR2A | P28223 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9844336 | 0.91 | GRM2 (0.56) | GRM2KCNH2HTR2AKDM4E | |
| SCHEMBL9677516 | 0.90 | SIGMAR1 (0.66) | SIGMAR1GRM2 | |
| SCHEMBL9844499 | 0.90 | HTR2A (0.53) | GRM2KCNH2HTR2AMEN1LMNA | |
| SCHEMBL9844433 | 0.88 | SIGMAR1 (0.45) | SIGMAR1GRM2KCNH2HTR2AKMT2A | |
| SCHEMBL9844242 | 0.87 | HTR2A (0.52) | GRM2HTR2AKDM4E | |
| SCHEMBL9844055 | 0.87 | GRM2 (0.49) | GRM2HTR1AKCNH2HTR2AMEN1 | |
| SCHEMBL9844167 | 0.85 | HTR7 (0.46) | HTR1AKCNH2HTR2AKMT2A | |
| SCHEMBL8799705 | 0.83 | GRM2 (0.56) | SIGMAR1GRM2 | |
| SCHEMBL9844308 | 0.83 | MAOA (0.56) | GRM2KCNH2HTR2AMEN1LMNA | |
| SCHEMBL9844291 | 0.83 | GRM2 (0.55) | SIGMAR1GRM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0443197-A2 | Oxazolidinones | MERCK PATENT GmbH (DE) | 1991-08-28 | — | — | EP | disclosed |