Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIF11 | P52732 | 8/20 | 0.44 |
| ▸ | CACNA1H | O95180 | 4/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | NT5E | P21589 | 1/20 | 0.37 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.37 |
| ▸ | CA12 | O43570 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | CA9 | Q16790 | 1/20 | 0.36 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9677317 | 0.89 | KIF11 (0.42) | KIF11CACNA1HKDM4EALDH1A1NT5E | |
| SCHEMBL9678806 | 0.88 | KIF11 (0.42) | KIF11RIPK1 | |
| SCHEMBL9676928 | 0.85 | CNR1 (0.42) | KIF11CACNA1HKDM4EALDH1A1CA1 | |
| SCHEMBL9676937 | 0.85 | RIPK1 (0.53) | KIF11CACNA1HKDM4EALDH1A1NT5E | |
| SCHEMBL9678347 | 0.81 | KIF11 (0.42) | KIF11CACNA1HKDM4EALDH1A1CA1 | |
| SCHEMBL9676962 | 0.81 | KIF11 (0.44) | KIF11ALDH1A1CA12CA1CA2 | |
| SCHEMBL9678774 | 0.81 | ALKBH2 (0.41) | KIF11CACNA1HKDM4EALDH1A1RIPK1 | |
| SCHEMBL9676007 | 0.78 | RIPK1 (0.36) | KIF11CACNA1HKDM4EALDH1A1NT5E | |
| SCHEMBL9678289 | 0.78 | KIF11 (0.36) | KIF11CACNA1HKDM4EALDH1A1NT5E | |
| SCHEMBL9676874 | 0.78 | NPC1 (0.53) | ALDH1A1RIPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0269141-B1 | 1-CARBAMOYL-2-PYRAZOLINE DERIVATIVES HAVING HERBICIDAL ACTIVITY | DUPHAR INTERNATIONAL RESEARCH B.V (NL) | 1992-09-16 | — | — | EP | disclosed |
| US-4927452-A | 1-carbonyl-2-pyrazoline derivatives having herbicidal activity | DUPHAR INTERNATIONAL RESEARCH B.V. (NL) | 1990-05-22 | — | — | US | disclosed |
| EP-0269141-A2 | 1-Carbamoyl-2-pyrazoline derivatives having herbicidal activity | DUPHAR INTERNATIONAL RESEARCH B.V (NL) | 1988-06-01 | — | — | EP | disclosed |