Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIF11 | P52732 | 7/20 | 0.42 |
| ▸ | STS | P08842 | 1/20 | 0.41 |
| ▸ | EGFR | P00533 | 1/20 | 0.38 |
| ▸ | CNR1 | P21554 | 3/20 | 0.38 |
| ▸ | CNR2 | P34972 | 2/20 | 0.37 |
| ▸ | YAP1 | P46937 | 1/20 | 0.37 |
| ▸ | TEAD4 | Q15561 | 1/20 | 0.37 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.36 |
| ▸ | HTR6 | P50406 | 1/20 | 0.36 |
| ▸ | MAOA | P21397 | 1/20 | 0.35 |
| ▸ | MAOB | P27338 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9676962 | 0.90 | KIF11 (0.44) | KIF11EGFRCNR1RIPK1HTR6 | |
| SCHEMBL9678694 | 0.88 | KIF11 (0.44) | KIF11RIPK1 | |
| SCHEMBL9676928 | 0.86 | CNR1 (0.42) | KIF11CNR1CNR2RIPK1 | |
| SCHEMBL9679224 | 0.84 | RIPK1 (0.54) | KIF11STSEGFRRIPK1HTR6 | |
| SCHEMBL9678347 | 0.82 | KIF11 (0.42) | KIF11CNR1RIPK1 | |
| SCHEMBL9677317 | 0.82 | KIF11 (0.42) | KIF11RIPK1 | |
| SCHEMBL9678774 | 0.79 | ALKBH2 (0.41) | KIF11RIPK1 | |
| SCHEMBL9678797 | 0.79 | RIPK1 (0.40) | RIPK1 | |
| SCHEMBL9676475 | 0.77 | POLB (0.59) | RIPK1HTR6 | |
| SCHEMBL9676007 | 0.77 | RIPK1 (0.36) | KIF11RIPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0269141-B1 | 1-CARBAMOYL-2-PYRAZOLINE DERIVATIVES HAVING HERBICIDAL ACTIVITY | DUPHAR INTERNATIONAL RESEARCH B.V (NL) | 1992-09-16 | — | — | EP | disclosed |
| US-4927452-A | 1-carbonyl-2-pyrazoline derivatives having herbicidal activity | DUPHAR INTERNATIONAL RESEARCH B.V. (NL) | 1990-05-22 | — | — | US | disclosed |
| EP-0269141-A2 | 1-Carbamoyl-2-pyrazoline derivatives having herbicidal activity | DUPHAR INTERNATIONAL RESEARCH B.V (NL) | 1988-06-01 | — | — | EP | disclosed |