Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCAR2 | Q8TDS4 | 9/20 | 0.69 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 3/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 5/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | CA12 | O43570 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | CA7 | P43166 | 1/20 | 0.36 |
| ▸ | CA9 | Q16790 | 1/20 | 0.36 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.36 |
| ▸ | MDM2 | Q00987 | 2/20 | 0.35 |
| ▸ | MDM4 | O15151 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Ethyl Fumarate SCHEMBL9678685 | 1.00 | HCAR2 (0.69) | HCAR2ALDH1A1LMNAHSD17B10MAPT | |
| Ethyl Fumarate SCHEMBL10900161 | 0.97 | HCAR2 (0.65) | HCAR2ALDH1A1LMNAHSD17B10MAPT | |
| Ethyl Fumarate SCHEMBL10899884 | 0.95 | HCAR2 (0.62) | HCAR2ALDH1A1LMNAHSD17B10MAPT | |
| Ethyl Fumarate SCHEMBL10897357 | 0.94 | HCAR2 (0.61) | HCAR2ALDH1A1LMNAHSD17B10MAPT | |
| Diethyl Maleate SCHEMBL11796378 | 0.93 | HCAR2 (0.55) | HCAR2ALDH1A1LMNAHSD17B10MAPT | |
| Maleic Acid SCHEMBL1766045 | 0.92 | HCAR2 (0.56) | HCAR2ALDH1A1LMNAHSD17B10MAPT | |
| SCHEMBL2358640 | 0.85 | MAPT (0.47) | HCAR2ALDH1A1MAPTATM | |
| SCHEMBL14723490 | 0.85 | MAPT (0.47) | HCAR2ALDH1A1MAPTATM | |
| SCHEMBL2358642 | 0.85 | MAPT (0.47) | HCAR2ALDH1A1MAPTATM | |
| Acrylic Acid Ethyl Ester SCHEMBL11043394 | 0.84 | HCAR2 (0.46) | HCAR2ALDH1A1LMNAHSD17B10MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0499957-A2 | Selectively soluble, protective coating compositions derived from vinyl acetate/monoalkyl maleate copolymers | AIR PRODUCTS AND CHEMICALS, INC. (US) | 1992-08-26 | — | — | EP | disclosed |