Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RECQL | P46063 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | RIPK1 | Q13546 | 5/20 | 0.34 |
| ▸ | HTR6 | P50406 | 3/20 | 0.34 |
| ▸ | KLK7 | P49862 | 1/20 | 0.33 |
| ▸ | EDNRA | P25101 | 2/20 | 0.33 |
| ▸ | EDNRB | P24530 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9677211 | 0.91 | RECQL (0.38) | RECQLPOLBMAPTRIPK1HTR6 | |
| SCHEMBL9678966 | 0.87 | MAPT (0.37) | MAPTRIPK1HTR6 | |
| SCHEMBL9678653 | 0.87 | HTR6 (0.46) | POLBHTR6 | |
| SCHEMBL9676071 | 0.84 | ALKBH2 (0.39) | POLB | |
| SCHEMBL9676531 | 0.84 | CA1 (0.41) | POLBMAPT | |
| SCHEMBL9676369 | 0.84 | HTR6 (0.44) | RIPK1HTR6 | |
| SCHEMBL9677678 | 0.83 | THRB (0.43) | — | |
| SCHEMBL9677207 | 0.83 | HTR6 (0.38) | HTR6 | |
| SCHEMBL9678674 | 0.83 | MAPT (0.40) | RECQLPOLBMAPTRIPK1KLK7 | |
| SCHEMBL9678709 | 0.79 | HTR6 (0.45) | POLBMAPTRIPK1HTR6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0269141-B1 | 1-CARBAMOYL-2-PYRAZOLINE DERIVATIVES HAVING HERBICIDAL ACTIVITY | DUPHAR INTERNATIONAL RESEARCH B.V (NL) | 1992-09-16 | — | — | EP | disclosed |
| US-4927452-A | 1-carbonyl-2-pyrazoline derivatives having herbicidal activity | DUPHAR INTERNATIONAL RESEARCH B.V. (NL) | 1990-05-22 | — | — | US | disclosed |
| EP-0269141-A2 | 1-Carbamoyl-2-pyrazoline derivatives having herbicidal activity | DUPHAR INTERNATIONAL RESEARCH B.V (NL) | 1988-06-01 | — | — | EP | disclosed |