Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | RIPK1 | Q13546 | 7/20 | 0.37 |
| ▸ | KLK7 | P49862 | 1/20 | 0.36 |
| ▸ | EDNRA | P25101 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | EDNRB | P24530 | 1/20 | 0.36 |
| ▸ | RECQL | P46063 | 2/20 | 0.35 |
| ▸ | CA12 | O43570 | 1/20 | 0.34 |
| ▸ | CA1 | P00915 | 1/20 | 0.34 |
| ▸ | CA2 | P00918 | 1/20 | 0.34 |
| ▸ | CA9 | Q16790 | 1/20 | 0.34 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9678547 | 0.86 | RIPK1 (0.39) | RIPK1POLBCA12CA1CA2 | |
| SCHEMBL9677343 | 0.86 | HTR6 (0.46) | MAPTRIPK1POLBCA12CA1 | |
| SCHEMBL9677211 | 0.85 | RECQL (0.38) | MAPTRIPK1KLK7EDNRAPOLB | |
| SCHEMBL9676497 | 0.83 | RIPK1 (0.52) | MAPTRIPK1POLB | |
| SCHEMBL9678698 | 0.83 | RECQL (0.39) | MAPTRIPK1KLK7EDNRAPOLB | |
| SCHEMBL9677191 | 0.82 | CA1 (0.45) | MAPTRIPK1POLBCA1CA2 | |
| SCHEMBL9675919 | 0.82 | ALKBH2 (0.43) | POLB | |
| SCHEMBL9675993 | 0.81 | THRB (0.47) | MAPTPOLBCA1CA2 | |
| SCHEMBL9677235 | 0.77 | HTR6 (0.44) | MAPTRIPK1POLB | |
| SCHEMBL9679257 | 0.77 | RIPK1 (0.36) | MAPTRIPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0269141-B1 | 1-CARBAMOYL-2-PYRAZOLINE DERIVATIVES HAVING HERBICIDAL ACTIVITY | DUPHAR INTERNATIONAL RESEARCH B.V (NL) | 1992-09-16 | — | — | EP | disclosed |
| US-4927452-A | 1-carbonyl-2-pyrazoline derivatives having herbicidal activity | DUPHAR INTERNATIONAL RESEARCH B.V. (NL) | 1990-05-22 | — | — | US | disclosed |
| EP-0269141-A2 | 1-Carbamoyl-2-pyrazoline derivatives having herbicidal activity | DUPHAR INTERNATIONAL RESEARCH B.V (NL) | 1988-06-01 | — | — | EP | disclosed |