Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RIPK1 | Q13546 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | CA5A | P35218 | 1/20 | 0.39 |
| ▸ | CA9 | Q16790 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | BCL2 | P10415 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | NR1H2 | P55055 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.38 |
| ▸ | SLC40A1 | Q9NP59 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9676811 | 0.87 | RIPK1 (0.56) | RIPK1NPC1GAACA1CA2 | |
| SCHEMBL9678347 | 0.84 | KIF11 (0.42) | RIPK1CA1CA2BCL2ALDH1A1 | |
| SCHEMBL9677317 | 0.84 | KIF11 (0.42) | RIPK1NPC1ALDH1A1POLB | |
| SCHEMBL9676962 | 0.84 | KIF11 (0.44) | RIPK1CA1CA2CA9ALDH1A1 | |
| SCHEMBL9676928 | 0.82 | CNR1 (0.42) | RIPK1CA1CA2KMT2AALDH1A1 | |
| SCHEMBL9678774 | 0.81 | ALKBH2 (0.41) | RIPK1KMT2AMEN1NR1H2ALDH1A1 | |
| SCHEMBL9676007 | 0.81 | RIPK1 (0.36) | RIPK1GAAALDH1A1SLC40A1 | |
| SCHEMBL9678289 | 0.81 | KIF11 (0.36) | RIPK1GAACA1CA2CA9 | |
| SCHEMBL9678822 | 0.80 | RIPK1 (0.54) | RIPK1NPC1KMT2AMEN1ALDH1A1 | |
| SCHEMBL9678806 | 0.79 | KIF11 (0.42) | RIPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0269141-B1 | 1-CARBAMOYL-2-PYRAZOLINE DERIVATIVES HAVING HERBICIDAL ACTIVITY | DUPHAR INTERNATIONAL RESEARCH B.V (NL) | 1992-09-16 | — | — | EP | disclosed |
| US-4927452-A | 1-carbonyl-2-pyrazoline derivatives having herbicidal activity | DUPHAR INTERNATIONAL RESEARCH B.V. (NL) | 1990-05-22 | — | — | US | disclosed |
| EP-0269141-A2 | 1-Carbamoyl-2-pyrazoline derivatives having herbicidal activity | DUPHAR INTERNATIONAL RESEARCH B.V (NL) | 1988-06-01 | — | — | EP | disclosed |