SCHEMBL9680047

SCHEMBL9680047

CN1CCc2c(C(=O)c3ccccc3)cccc21

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MGLL Q99685 1/20 0.48
AKR1C3 P42330 2/20 0.47
MYC P01106 1/20 0.47
ALDH1A1 P00352 2/20 0.45
NPSR1 Q6W5P4 2/20 0.45
HSP90AA1 P07900 1/20 0.45
PKM P14618 1/20 0.45
CCR6 P51684 1/20 0.45
ATM Q13315 1/20 0.45
TLR9 Q9NR96 1/20 0.45
TDP1 Q9NUW8 1/20 0.45
GAA P10253 2/20 0.42
SMN1; SMN2 Q16637 1/20 0.42
POLB P06746 2/20 0.42
MAPT P10636 1/20 0.41
NOTUM Q6P988 3/20 0.41
DRD2 P14416 1/20 0.41
DRD1 P21728 1/20 0.41
DRD3 P35462 1/20 0.41
HPGD P15428 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28494012 0.77 MYC (0.46) MGLLMYCALDH1A1ATMSMN1; SMN2
SCHEMBL11471262 0.76 ALDH1A1 (0.45) AKR1C3MYCALDH1A1TDP1GAA
SCHEMBL2733549 0.75 TNKS (0.49) MGLLMYCALDH1A1GAASMN1; SMN2
SCHEMBL22140429 0.74 KMT2A (0.49) MGLLAKR1C3MYCALDH1A1GAA
SCHEMBL28578536 0.73 LMNA (0.51) AKR1C3MYCALDH1A1NPSR1HSP90AA1
SCHEMBL10622624 0.70 ALDH1A1 (0.56) AKR1C3ALDH1A1NPSR1ATMTDP1
SCHEMBL242419 0.70 AKR1C3 (0.57) AKR1C3ALDH1A1ATMTDP1GAA
SCHEMBL257381 0.70 KDM4E (0.42) MGLLALDH1A1NPSR1GAASMN1; SMN2
SCHEMBL94532 0.70 DRD2 (0.46) MGLLNOTUMDRD2DRD1DRD3
SCHEMBL11131477 0.69 AKR1C3 (0.50) AKR1C3ALDH1A1NPSR1HSP90AA1PKM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5082937-A Gastrin or cholecystokinin antagonists JOUVEINAL S.A. (FR) 1992-01-21 US disclosed
EP-0420716-A2 Benzodiazepines, process and intermediates for their preparation and their therapeutic use JOUVEINAL S.A. (FR) 1991-04-03 EP disclosed