Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.50 |
| ▸ | MAPT | P10636 | 3/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | SCN3A | Q9NY46 | 2/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | MC4R | P32245 | 1/20 | 0.50 |
| ▸ | SCN4A | P35499 | 1/20 | 0.50 |
| ▸ | MC3R | P41968 | 1/20 | 0.50 |
| ▸ | HTR3A | P46098 | 1/20 | 0.50 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.50 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 3/20 | 0.49 |
| ▸ | BLM | P54132 | 2/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | MTOR | P42345 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 6/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9680693 | 0.87 | TDP1 (0.51) | LMNAMAPTALDH1A1SCN3ACYP3A4 | |
| SCHEMBL9680221 | 0.85 | KMT2A (0.49) | LMNATDP1MTORMEN1KMT2A | |
| SCHEMBL22414266 | 0.73 | MTOR (0.49) | LMNAMAPTALDH1A1SCN3ACYP3A4 | |
| SCHEMBL23317213 | 0.72 | BRD4 (0.60) | LMNAMAPTALDH1A1SCN3ACYP3A4 | |
| SCHEMBL9851048 | 0.71 | KMT2A (0.54) | LMNATDP1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL9680252 | 0.70 | LPAR1 (0.58) | LMNAMAPTALDH1A1MAPK1GAA | |
| SCHEMBL9680261 | 0.70 | CYP2C19 (0.54) | LMNAMAPTALDH1A1CYP3A4TDP1 | |
| SCHEMBL6243519 | 0.70 | MAPT (0.70) | LMNAMAPTALDH1A1SCN3ACYP3A4 | |
| SCHEMBL9679595 | 0.69 | NLRP3 (0.49) | MEN1KMT2ASMN1; SMN2 | |
| Lidofenin SCHEMBL214472 | 0.69 | MAPT (0.73) | LMNAMAPTALDH1A1SCN3ACYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5153226-A | Administering as anticholesterol agents, for atherosclerosis | WARNER-LAMBERT COMPANY (US) | 1992-10-06 | — | — | US | disclosed |