Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.51 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.51 |
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.51 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | MC4R | P32245 | 1/20 | 0.50 |
| ▸ | SCN4A | P35499 | 1/20 | 0.50 |
| ▸ | MC3R | P41968 | 1/20 | 0.50 |
| ▸ | HTR3A | P46098 | 1/20 | 0.50 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.50 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.50 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 2/20 | 0.49 |
| ▸ | BLM | P54132 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9680185 | 0.87 | LMNA (0.50) | TDP1ALOX15CYP2C19ALDH1A1LMNA | |
| SCHEMBL9680261 | 0.82 | CYP2C19 (0.54) | TDP1ALOX15TSHRCYP2C19HIF1A | |
| SCHEMBL9680634 | 0.74 | ALOX15 (0.46) | TDP1ALOX15TSHRCYP2C19HIF1A | |
| SCHEMBL9680221 | 0.73 | KMT2A (0.49) | TDP1LMNAMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL22414266 | 0.73 | MTOR (0.49) | TDP1CYP2C19ALDH1A1LMNAMAPT | |
| SCHEMBL10710911 | 0.72 | ALDH1A1 (0.82) | TDP1ALOX15TSHRCYP2C19HIF1A | |
| SCHEMBL12812272 | 0.70 | POLB (0.65) | TDP1ALOX15TSHRCYP2C19HIF1A | |
| SCHEMBL23317213 | 0.70 | BRD4 (0.60) | ALOX15CYP2C19ALDH1A1LMNAMAPT | |
| Lidocaine SCHEMBL28313393 | 0.70 | MAPT (0.97) | TDP1ALOX15TSHRCYP2C19HIF1A | |
| SCHEMBL12923166 | 0.69 | POLB (0.64) | TDP1ALOX15CYP2C19ALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0415413-A1 | Acat inhibitors | WARNER-LAMBERT COMPANY (US) | 1991-03-06 | — | — | EP | claimed |
| US-5153226-A | Administering as anticholesterol agents, for atherosclerosis | WARNER-LAMBERT COMPANY (US) | 1992-10-06 | — | — | US | disclosed |
| EP-0415413-A1 | Acat inhibitors | WARNER-LAMBERT COMPANY (US) | 1991-03-06 | — | — | EP | disclosed |