Lidofenin

Lidofenin

SCHEMBL214472

Cc1cccc(C)c1NC(=O)CN(CC(=O)O)CC(=O)O

nearest known ligand 0.73

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 3/20 0.73
LMNA P02545 3/20 0.73
SCN3A Q9NY46 3/20 0.73
ALDH1A1 P00352 1/20 0.73
CYP3A4 P08684 1/20 0.73
MAPK1 P28482 1/20 0.73
MC4R P32245 1/20 0.73
SCN4A P35499 1/20 0.73
MC3R P41968 1/20 0.73
HTR3A P46098 1/20 0.73
SCN5A Q14524 1/20 0.73
SCN9A Q15858 1/20 0.73
GAA P10253 2/20 0.71
BLM P54132 2/20 0.71
CYP2C19 P33261 2/20 0.69
TDP1 Q9NUW8 2/20 0.69
ALOX15 P16050 2/20 0.69
TSHR P16473 1/20 0.69
HIF1A Q16665 1/20 0.69
DRD3 P35462 1/20 0.58

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Lidofenin SCHEMBL28279278 0.98 MAPT (0.71) MAPTLMNASCN3AALDH1A1CYP3A4
Lidofenin SCHEMBL29765217 0.98 MAPT (0.71) MAPTLMNASCN3AALDH1A1CYP3A4
Edetic Acid SCHEMBL17899413 0.88 MAPT (0.81) MAPTLMNASCN3AALDH1A1CYP3A4
Lidocaine SCHEMBL28313393 0.87 MAPT (0.97) MAPTLMNASCN3AALDH1A1CYP3A4
Lidocaine SCHEMBL28651403 0.86 MAPT (0.88) MAPTLMNASCN3AALDH1A1CYP3A4
Lidocaine SCHEMBL27245471 0.86 MAPT (0.88) MAPTLMNASCN3AALDH1A1CYP3A4
Lidocaine SCHEMBL22188608 0.85 MAPT (0.94) MAPTLMNASCN3AALDH1A1CYP3A4
Lidocaine SCHEMBL8183082 0.85 MAPT (1.00) MAPTLMNASCN3AALDH1A1CYP3A4
Lidocaine SCHEMBL5334354 0.85 MAPT (1.00) MAPTLMNASCN3AALDH1A1CYP3A4
Lidocaine SCHEMBL15689 0.85 MAPT (1.00) MAPTLMNASCN3AALDH1A1CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1749 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260137621-A1 ORALLY BIOAVAILABLE LIPID-BASED CONSTRUCTS DIASOME PHARMACEUTICALS INC (US) 2026-05-21 US claimed
EP-3977137-B1 DETECTION OF ANALYTES BY NANOPORE WITHOUT USING ELECTRODES NANJING UNIVERSITY (CN) 2026-04-01 EP claimed
US-20260071943-A1 METHOD FOR RECOVERING EXTRACELLULAR VESICLES H.U. GROUP RESEARCH INSTITUTE G.K. (JP) 2026-03-12 US claimed
US-12571110-B2 Metal sulfide scale dissolver for oilfield application HALLIBURTON ENERGY SERVICES, INC. (US) 2026-03-10 US claimed
EP-4696334-A2 FIBROBLAST ACTIVATION PROTEIN TARGETED COMPOUNDS AND USE THEREOF Perspective Therapeutics, Inc. (US) 2026-02-18 EP claimed
US-12552981-B2 Filter cake removal treatment fluid with chelating agent and viscoelastic surfactant SAUDI ARABIAN OIL COMPANY (SA) 2026-02-17 US claimed
US-20250376614-A1 FILTER CAKE REMOVAL TREATMENT FLUID WITH CHELATING AGENT AND VISCOELASTIC SURFACTANT SAUDI ARABIAN OIL CO (SA) 2025-12-11 US claimed
EP-4619043-A1 FIBROBLAST ACTIVATION PROTEIN TARGETED COMPOUNDS AND USE THEREOF Perspective Therapeutics, Inc. (US) 2025-09-24 EP claimed
US-20250288521-A1 ORALLY BIOAVAILABLE LIPID-BASED CONSTRUCTS DIASOME PHARMACEUTICALS INC (US) 2025-09-18 US claimed
US-12365945-B2 Urinary microbiomic profiling Convergent Genomics, Inc. (US) 2025-07-22 US claimed
US-20060024365-A1 Novel dosage form VAYA NAVIN 2006-02-02 US claimed
US-20060018933-A1 Novel drug delivery system TORRENT PHARMACEUTICALS LIMITED (IN) 2006-01-26 US claimed
US-20060018934-A1 Novel drug delivery system TORRENT PHARMACEUTICALS LIMITED (IN) 2006-01-26 US claimed
EP-0999855-A1 POLYMER BASED PHARMACEUTICAL COMPOSITIONS FOR TARGETED DELIVERY OF BIOLOGICALLY ACTIVE AGENTS SDG, Inc. (US) 2000-05-17 EP claimed
US-6063400-A CARRIER; DIAGNOSTIC OR THERAPEUTIC AGENT AND SEQUESTERING AGENT SDG, INC. (US) 2000-05-16 US claimed
WO-1999004824-A1 POLYMER BASED PHARMACEUTICAL COMPOSITIONS FOR TARGETED DELIVERY OF BIOLOGICALLY ACTIVE AGENTS SDG, INC. (US) 1999-02-04 WO claimed
EP-0166746-B1 PREPARATION OF ?99M TC RADIOPHARMACEUTICALS THE COMMONWEALTH OF AUSTRALIA (AU) 1991-04-24 EP claimed
EP-0165728-B1 NMR CONTRAST AGENTS NYCOMED AS (NO) 1988-12-14 EP claimed
US-4714607-A NUCLEAR MAGNETIC RESONANCE NYCOMED AS (NO) 1987-12-22 US claimed
US-4272503-A FORMING A STABLE COMPLEX OF LIGAND AND TECHNETIUM BY THE REDUCTION OF PERTECHNETATE BY A SUBSTRATE-CHELATE-REDUCING AGENT COMPLEX; LABELS; RADIOLOGY NEW ENGLAND NUCLEAR CORPORATION (US) 1981-06-09 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12552981-B2 Filter cake removal treatment fluid with chelating agent and viscoelastic surfactant DKK1, PROC, SHH MAPT 3494/4885LMNA 2613/4885SCN3A 2576/4885
US-20250288521-A1 ORALLY BIOAVAILABLE LIPID-BASED CONSTRUCTS FABP2, FABP1, FABP6 MAPT 3275/4885LMNA 1568/4885SCN3A 2840/4885
US-20260071943-A1 METHOD FOR RECOVERING EXTRACELLULAR VESICLES EXOSC5, EXOSC9, EXOSC10 MAPT 2626/4885LMNA 2620/4885SCN3A 2338/4885
US-20260137621-A1 ORALLY BIOAVAILABLE LIPID-BASED CONSTRUCTS FABP2, FABP1, SGMS2 MAPT 3628/4885LMNA 1721/4885SCN3A 552/4885
US-12571110-B2 Metal sulfide scale dissolver for oilfield application HKDC1, SLC7A11, DDHD2 MAPT 2615/4885LMNA 2373/4885SCN3A 2331/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.